Abstract
Diffuse neurofibroma is an uncommon variant of neurofibroma that usually presents on the head and neck. It is common in children and young adults. Clinically, the lesion presents as large, poorly circumscribed swelling. A 25 year-old female presented with diffuse swelling on the occipital region of the scalp for several years. Magnetic resonance imaging showed 8×9 cm sized, ill defined infiltration on the occipital scalp. The histologic examination revealed unencapsulated loosely arranged spindle cells within the dermis and subcutaneous tissue. Meissnerian differentiation was observed within the tumor cells. The tumor cells were positive for S-100 protein. We report a case of diffuse neurofibroma on the occipital region of the scalp.
| Original language | English |
|---|---|
| Pages (from-to) | 355-358 |
| Number of pages | 4 |
| Journal | Korean Journal of Dermatology |
| Volume | 46 |
| Issue number | 3 |
| State | Published - 2008 |
Bibliographical note
Funding Information:The authors hope to express their gratitude to Universiti Malaysia Pahang , the Faculty of Chemical and Process Engineering Technology, College of Engineering Technology for ongoing supporting the necessary lab facilities and financial assistance under grants postgraduate research scheme ( PGRS1903102 & RDU170352 ). The authors also hope to express their appreciation of Petronas Penapisan Terengganu, Malaysia's assistance in supplying crude oil samples used in this study.
Keywords
- Diffuse neurofibroma
- Occipital scalp