A case of erythema elevatum diutinum with multiple myeloma

Erythema elevatum diutinum (EED) is a rare, chronic inflammatory skin disease of unknown etiology. Clinical findings involve symmetrical livid-erythematous to red-brown papules and plaques or nodules. The skin lesions are located over extensor surfaces and often over joints. Histological findings are characterized by leukocytoclastic vasculitis and dense neutrophilic infiltration in the early stages of the lesions and by fibrosis in the late stages. EED may be associated with several hematological disorders, infectious diseases, immunological disorders, and certain malignancies. We report on a 59-year-old man with EED associated with multiple myeloma.