A practical utility and benefit of pharmacogenetic-based antidepressant treatment strategy for major depressive disorder patients with difficult-to-treat

  • Kyung Ho Lee
  • , Won Myong Bahk
  • , Soo Jung Lee
  • , Alessandro Serretti
  • , Chi Un Pae

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Objective: We report the results of pharmacogenomics-based antidepressant treatment (PGXt) results in treating treatment- resistant major depressive disorder (TRD) patients in real practice. Methods: Nine patients were prescribed Neuropharmagen? for selection of antidepressants for individual patient and their clinical outcomes were followed. Results: After treatment by PGXt results from current antidepressants, substantial reduction of depressive symptoms was observed at some point and maintained during observation period in six patients. Conclusion: Our case series potentially shows the clinical utility and benefit of PGXt for treatment of TRD patients.

Original languageEnglish
Pages (from-to)160-165
Number of pages6
JournalClinical Psychopharmacology and Neuroscience
Volume19
Issue number1
DOIs
StatePublished - Feb 2021

Bibliographical note

Publisher Copyright:
© 2021 Korean College of Neuropsychopharmacology. All rights reserved.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Antidepressive agent
  • Clinical outcome
  • Depressive disorder
  • Treatment
  • Treatment-resistance

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