Aberration of cholesterol level in first-onset bipolar I patients

Chi Un Pae; Jung Jin Kim; Soo Jung Lee; Chul Lee; In Ho Paik; Chang Uk Lee

doi:10.1016/j.jad.2004.04.010

Aberration of cholesterol level in first-onset bipolar I patients

Chi Un Pae
, Jung Jin Kim
, Soo Jung Lee
, Chul Lee
, In Ho Paik
, Chang Uk Lee

Department of Psychiatry

The Catholic University of Korea, College of Medicine

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Cholesterol interacts with serotonin and it has been found to be associated with some clinical symptoms of mood disorders. There is a paucity of data on first-onset bipolar patients and from Asian population. The total cholesterol (TC) level was examined in 25 bipolar I patients with a single manic episode (BPSM) and 30 controls. The TC level was significantly lower in the BPSM than in the controls. There were negative correlations between the Young mania rating scale (YMRS) scores and the pretreatment TC level in BPSM. This study suggests that the TC level can be changed after treatment in bipolar manic patients, although more studies involving different ethnic groups will be needed.

Original language	English
Pages (from-to)	79-82
Number of pages	4
Journal	Journal of Affective Disorders
Volume	83
Issue number	1
DOIs	https://doi.org/10.1016/j.jad.2004.04.010
State	Published - 15 Nov 2004

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Asian
Cholesterol
Mania

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10.1016/j.jad.2004.04.010

Cite this

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title = "Aberration of cholesterol level in first-onset bipolar I patients",

abstract = "Cholesterol interacts with serotonin and it has been found to be associated with some clinical symptoms of mood disorders. There is a paucity of data on first-onset bipolar patients and from Asian population. The total cholesterol (TC) level was examined in 25 bipolar I patients with a single manic episode (BPSM) and 30 controls. The TC level was significantly lower in the BPSM than in the controls. There were negative correlations between the Young mania rating scale (YMRS) scores and the pretreatment TC level in BPSM. This study suggests that the TC level can be changed after treatment in bipolar manic patients, although more studies involving different ethnic groups will be needed.",

keywords = "Asian, Cholesterol, Mania",

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doi = "10.1016/j.jad.2004.04.010",

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T1 - Aberration of cholesterol level in first-onset bipolar I patients

AU - Pae, Chi Un

AU - Kim, Jung Jin

AU - Lee, Soo Jung

AU - Lee, Chul

AU - Paik, In Ho

AU - Lee, Chang Uk

PY - 2004/11/15

Y1 - 2004/11/15

N2 - Cholesterol interacts with serotonin and it has been found to be associated with some clinical symptoms of mood disorders. There is a paucity of data on first-onset bipolar patients and from Asian population. The total cholesterol (TC) level was examined in 25 bipolar I patients with a single manic episode (BPSM) and 30 controls. The TC level was significantly lower in the BPSM than in the controls. There were negative correlations between the Young mania rating scale (YMRS) scores and the pretreatment TC level in BPSM. This study suggests that the TC level can be changed after treatment in bipolar manic patients, although more studies involving different ethnic groups will be needed.

AB - Cholesterol interacts with serotonin and it has been found to be associated with some clinical symptoms of mood disorders. There is a paucity of data on first-onset bipolar patients and from Asian population. The total cholesterol (TC) level was examined in 25 bipolar I patients with a single manic episode (BPSM) and 30 controls. The TC level was significantly lower in the BPSM than in the controls. There were negative correlations between the Young mania rating scale (YMRS) scores and the pretreatment TC level in BPSM. This study suggests that the TC level can be changed after treatment in bipolar manic patients, although more studies involving different ethnic groups will be needed.

KW - Asian

KW - Cholesterol

KW - Mania

UR - https://www.scopus.com/pages/publications/8444226811

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DO - 10.1016/j.jad.2004.04.010

M3 - Article

C2 - 15546649

AN - SCOPUS:8444226811

SN - 0165-0327

VL - 83

SP - 79

EP - 82

JO - Journal of Affective Disorders

JF - Journal of Affective Disorders

IS - 1

ER -

Aberration of cholesterol level in first-onset bipolar I patients

Abstract

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Keywords

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