Antifungal susceptibility to amphotericin B, fluconazole, voriconazole, and flucytosine in Candida bloodstream isolates from 15 tertiary hospitals in Korea

Sook In Jung; Jong Hee Shin; Hyun Jung Choi; Min Young Ju; Soo Hyun Kim; Wee Gyo Lee; Yeon Joon Park; Kyungwon Lee

doi:10.3343/alm.2012.32.6.426

Antifungal susceptibility to amphotericin B, fluconazole, voriconazole, and flucytosine in Candida bloodstream isolates from 15 tertiary hospitals in Korea

Sook In Jung
, Jong Hee Shin
, Hyun Jung Choi
, Min Young Ju
, Soo Hyun Kim
, Wee Gyo Lee
, Yeon Joon Park
, Kyungwon Lee

Department of Laboratory Medicine

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

The in vitro antifungal susceptibility of 636 Candida bloodstream isolates collected from 15 tertiary hospitals in Korea was determined using the Vitek-2 yeast susceptibility system (bioMérieux, France). Overall susceptibility rates were 98.1%, 95.9%, 99.1%, and 97.3% for amphotericin B, fluconazole, voriconazole, and flucytosine, respectively. The results show that the rates of resistance to 4 antifungal drugs remain low among Candida bloodstream isolates in Korea.

Original language	English
Pages (from-to)	426-428
Number of pages	3
Journal	Annals of Laboratory Medicine
Volume	32
Issue number	6
DOIs	https://doi.org/10.3343/alm.2012.32.6.426
State	Published - Nov 2012

Keywords

Amphotericin B
Candida
Fluconazole
Flucytosine
Voriconazole

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10.3343/alm.2012.32.6.426

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@article{7756fe74603a46158e571cf907565db8,

title = "Antifungal susceptibility to amphotericin B, fluconazole, voriconazole, and flucytosine in Candida bloodstream isolates from 15 tertiary hospitals in Korea",

abstract = "The in vitro antifungal susceptibility of 636 Candida bloodstream isolates collected from 15 tertiary hospitals in Korea was determined using the Vitek-2 yeast susceptibility system (bioM{\'e}rieux, France). Overall susceptibility rates were 98.1\%, 95.9\%, 99.1\%, and 97.3\% for amphotericin B, fluconazole, voriconazole, and flucytosine, respectively. The results show that the rates of resistance to 4 antifungal drugs remain low among Candida bloodstream isolates in Korea.",

keywords = "Amphotericin B, Candida, Fluconazole, Flucytosine, Voriconazole",

author = "Jung, \{Sook In\} and Shin, \{Jong Hee\} and Choi, \{Hyun Jung\} and Ju, \{Min Young\} and Kim, \{Soo Hyun\} and Lee, \{Wee Gyo\} and Park, \{Yeon Joon\} and Kyungwon Lee",

year = "2012",

month = nov,

doi = "10.3343/alm.2012.32.6.426",

language = "English",

volume = "32",

pages = "426--428",

journal = "Annals of Laboratory Medicine",

issn = "2234-3806",

publisher = "Korean Society for Laboratory Medicine",

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}

TY - JOUR

T1 - Antifungal susceptibility to amphotericin B, fluconazole, voriconazole, and flucytosine in Candida bloodstream isolates from 15 tertiary hospitals in Korea

AU - Jung, Sook In

AU - Shin, Jong Hee

AU - Choi, Hyun Jung

AU - Ju, Min Young

AU - Kim, Soo Hyun

AU - Lee, Wee Gyo

AU - Park, Yeon Joon

AU - Lee, Kyungwon

PY - 2012/11

Y1 - 2012/11

N2 - The in vitro antifungal susceptibility of 636 Candida bloodstream isolates collected from 15 tertiary hospitals in Korea was determined using the Vitek-2 yeast susceptibility system (bioMérieux, France). Overall susceptibility rates were 98.1%, 95.9%, 99.1%, and 97.3% for amphotericin B, fluconazole, voriconazole, and flucytosine, respectively. The results show that the rates of resistance to 4 antifungal drugs remain low among Candida bloodstream isolates in Korea.

AB - The in vitro antifungal susceptibility of 636 Candida bloodstream isolates collected from 15 tertiary hospitals in Korea was determined using the Vitek-2 yeast susceptibility system (bioMérieux, France). Overall susceptibility rates were 98.1%, 95.9%, 99.1%, and 97.3% for amphotericin B, fluconazole, voriconazole, and flucytosine, respectively. The results show that the rates of resistance to 4 antifungal drugs remain low among Candida bloodstream isolates in Korea.

KW - Amphotericin B

KW - Candida

KW - Fluconazole

KW - Flucytosine

KW - Voriconazole

UR - https://www.scopus.com/pages/publications/84868556629

U2 - 10.3343/alm.2012.32.6.426

DO - 10.3343/alm.2012.32.6.426

M3 - Article

C2 - 23130342

AN - SCOPUS:84868556629

SN - 2234-3806

VL - 32

SP - 426

EP - 428

JO - Annals of Laboratory Medicine

JF - Annals of Laboratory Medicine

IS - 6

ER -

Antifungal susceptibility to amphotericin B, fluconazole, voriconazole, and flucytosine in Candida bloodstream isolates from 15 tertiary hospitals in Korea

Abstract

Keywords

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