Atypical disseminated skeletal tuberculosis mimicking metastasis on PET-CT and MRI

Seong Woo Go; Hea Yon Lee; Chae Hun Lim; Won Hee Jee; Young Pil Wang; Ie Ryung Yoo; Ji Young Kang

doi:10.2169/internalmedicine.51.8347

Atypical disseminated skeletal tuberculosis mimicking metastasis on PET-CT and MRI

Seong Woo Go, Hea Yon Lee, Chae Hun Lim, Won Hee Jee, Young Pil Wang, Ie Ryung Yoo, Ji Young Kang

Daegu Catholic University School of Medicine

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Multifocal skeletal tuberculosis is a very rare manifestation of tuberculous infection. The multiple bone lesions of multifocal skeletal tuberculosis are difficult to differentiate from metastasis, even when performing 2-[fluorine-18]-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (FDG PET/CT) or magnetic resonance imaging (MRI). A 25-year-old man presented with an abnormal chest X-ray. Radiologically, there were extensive osteolytic lesions on the skull, along the entire spine and on the ribs and both iliac bones,suggesting a diagnosis of bone metastasis. On FDG PET/CT, intensely increased F-18 FDG lesions were observed.A bone biopsy with a microbiologic study revealed a tuberculous infection. Follow-up PET/CT performed after treatment showed marked improvement in the extensive FDG uptake lesions

Original language	English
Pages (from-to)	2961-2965
Number of pages	5
Journal	Internal Medicine
Volume	51
Issue number	20
DOIs	https://doi.org/10.2169/internalmedicine.51.8347
State	Published - 2012

Keywords

Metastasis
Osteoarticular
PET/CT scan
Spinal tuberculosis
Tuberculosis
Whole spine MRI

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2169/internalmedicine.51.8347

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title = "Atypical disseminated skeletal tuberculosis mimicking metastasis on PET-CT and MRI",

abstract = "Multifocal skeletal tuberculosis is a very rare manifestation of tuberculous infection. The multiple bone lesions of multifocal skeletal tuberculosis are difficult to differentiate from metastasis, even when performing 2-[fluorine-18]-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (FDG PET/CT) or magnetic resonance imaging (MRI). A 25-year-old man presented with an abnormal chest X-ray. Radiologically, there were extensive osteolytic lesions on the skull, along the entire spine and on the ribs and both iliac bones,suggesting a diagnosis of bone metastasis. On FDG PET/CT, intensely increased F-18 FDG lesions were observed.A bone biopsy with a microbiologic study revealed a tuberculous infection. Follow-up PET/CT performed after treatment showed marked improvement in the extensive FDG uptake lesions",

keywords = "Metastasis, Osteoarticular, PET/CT scan, Spinal tuberculosis, Tuberculosis, Whole spine MRI",

author = "Go, {Seong Woo} and Lee, {Hea Yon} and Lim, {Chae Hun} and Jee, {Won Hee} and Wang, {Young Pil} and Yoo, {Ie Ryung} and Kang, {Ji Young}",

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T1 - Atypical disseminated skeletal tuberculosis mimicking metastasis on PET-CT and MRI

AU - Go, Seong Woo

AU - Lee, Hea Yon

AU - Lim, Chae Hun

AU - Jee, Won Hee

AU - Wang, Young Pil

AU - Yoo, Ie Ryung

AU - Kang, Ji Young

PY - 2012

Y1 - 2012

N2 - Multifocal skeletal tuberculosis is a very rare manifestation of tuberculous infection. The multiple bone lesions of multifocal skeletal tuberculosis are difficult to differentiate from metastasis, even when performing 2-[fluorine-18]-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (FDG PET/CT) or magnetic resonance imaging (MRI). A 25-year-old man presented with an abnormal chest X-ray. Radiologically, there were extensive osteolytic lesions on the skull, along the entire spine and on the ribs and both iliac bones,suggesting a diagnosis of bone metastasis. On FDG PET/CT, intensely increased F-18 FDG lesions were observed.A bone biopsy with a microbiologic study revealed a tuberculous infection. Follow-up PET/CT performed after treatment showed marked improvement in the extensive FDG uptake lesions

AB - Multifocal skeletal tuberculosis is a very rare manifestation of tuberculous infection. The multiple bone lesions of multifocal skeletal tuberculosis are difficult to differentiate from metastasis, even when performing 2-[fluorine-18]-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (FDG PET/CT) or magnetic resonance imaging (MRI). A 25-year-old man presented with an abnormal chest X-ray. Radiologically, there were extensive osteolytic lesions on the skull, along the entire spine and on the ribs and both iliac bones,suggesting a diagnosis of bone metastasis. On FDG PET/CT, intensely increased F-18 FDG lesions were observed.A bone biopsy with a microbiologic study revealed a tuberculous infection. Follow-up PET/CT performed after treatment showed marked improvement in the extensive FDG uptake lesions

KW - Metastasis

KW - Osteoarticular

KW - PET/CT scan

KW - Spinal tuberculosis

KW - Tuberculosis

KW - Whole spine MRI

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Atypical disseminated skeletal tuberculosis mimicking metastasis on PET-CT and MRI

Abstract

Keywords

UN SDGs

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