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Brain Iron Imaging in Aging and Cognitive Disorders: MRI Approaches

    • Hankuk University of Foreign Studies

    Research output: Contribution to journalReview articlepeer-review

    1 Scopus citations

    Abstract

    Iron has a vital role in the human body, including the central nervous system. Increased deposition of iron in the brain has been reported in aging and important neurodegenerative diseases. Owing to the unique magnetic resonance properties of iron, MRI has great potential for in vivo assessment of iron deposition, distribution, and non-invasive quantification. In this paper, we will review the MRI methods for iron assessment and their changes in aging and neurodegenerative diseases, focusing on Alzheimer's disease. In addition, we will summarize the limitations of current approaches and introduce new areas and MRI methods for iron imaging that are expected in the future.

    Original languageEnglish
    Pages (from-to)527-537
    Number of pages11
    JournalJournal of the Korean Society of Radiology (South Korea)
    Volume83
    Issue number3
    DOIs
    StatePublished - May 2022

    Bibliographical note

    Publisher Copyright:
    © 2022 The Korean Society of Radiology

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

    Keywords

    • Aging
    • Alzheimer Disease
    • Iron
    • Magnetic Resonance Imaging
    • Vascular Dementia

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