Case Report: Acute promyelocytic leukemia with +der(17)t(15;17) detected by fluorescence in situ hybridization (FISH)

Myungshin Kim; Jihyang Lim; Yonggoo Kim; Kyungja Han; Seok Lee; Kee Min Chang

Case Report: Acute promyelocytic leukemia with +der(17)t(15;17) detected by fluorescence in situ hybridization (FISH)

Myungshin Kim, Jihyang Lim, Yonggoo Kim, Kyungja Han, Seok Lee, Kee Min Chang

Research output: Contribution to journal › Article › peer-review

Abstract

We describe an unusual case of acute promyelocytic leukemia with +der(17)t(15;17) as the additional cytogenetic abnormality and with t(15;17) defined by fluorescence in situ hybridization (FISH) using a PML/RARA dual color, dual fusion translocation probe. By performing a step-by-step, complementary approach to evaluate unusual chromosomal abnormalities, we detected RARA/PML fusion on a marker chromosome similar to chromosome 17.

Original language	English
Pages (from-to)	195-198
Number of pages	4
Journal	Annals of Clinical and Laboratory Science
Volume	35
Issue number	2
State	Published - Mar 2005

Keywords

Acute promyelocytic leukemia
Fluorescence in situ hybridization
PML/RARA
RARA/PML

Cite this

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title = "Case Report: Acute promyelocytic leukemia with +der(17)t(15;17) detected by fluorescence in situ hybridization (FISH)",

abstract = "We describe an unusual case of acute promyelocytic leukemia with +der(17)t(15;17) as the additional cytogenetic abnormality and with t(15;17) defined by fluorescence in situ hybridization (FISH) using a PML/RARA dual color, dual fusion translocation probe. By performing a step-by-step, complementary approach to evaluate unusual chromosomal abnormalities, we detected RARA/PML fusion on a marker chromosome similar to chromosome 17.",

keywords = "Acute promyelocytic leukemia, Fluorescence in situ hybridization, PML/RARA, RARA/PML",

author = "Myungshin Kim and Jihyang Lim and Yonggoo Kim and Kyungja Han and Seok Lee and Chang, \{Kee Min\}",

year = "2005",

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T2 - Acute promyelocytic leukemia with +der(17)t(15;17) detected by fluorescence in situ hybridization (FISH)

AU - Kim, Myungshin

AU - Lim, Jihyang

AU - Kim, Yonggoo

AU - Han, Kyungja

AU - Lee, Seok

AU - Chang, Kee Min

PY - 2005/3

Y1 - 2005/3

N2 - We describe an unusual case of acute promyelocytic leukemia with +der(17)t(15;17) as the additional cytogenetic abnormality and with t(15;17) defined by fluorescence in situ hybridization (FISH) using a PML/RARA dual color, dual fusion translocation probe. By performing a step-by-step, complementary approach to evaluate unusual chromosomal abnormalities, we detected RARA/PML fusion on a marker chromosome similar to chromosome 17.

AB - We describe an unusual case of acute promyelocytic leukemia with +der(17)t(15;17) as the additional cytogenetic abnormality and with t(15;17) defined by fluorescence in situ hybridization (FISH) using a PML/RARA dual color, dual fusion translocation probe. By performing a step-by-step, complementary approach to evaluate unusual chromosomal abnormalities, we detected RARA/PML fusion on a marker chromosome similar to chromosome 17.

KW - Acute promyelocytic leukemia

KW - Fluorescence in situ hybridization

KW - PML/RARA

KW - RARA/PML

UR - https://www.scopus.com/pages/publications/18744378016

M3 - Article

C2 - 15943185

AN - SCOPUS:18744378016

SN - 0091-7370

VL - 35

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JO - Annals of Clinical and Laboratory Science

JF - Annals of Clinical and Laboratory Science

IS - 2

ER -

Case Report: Acute promyelocytic leukemia with +der(17)t(15;17) detected by fluorescence in situ hybridization (FISH)

Abstract

Keywords

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