Cerebrovascular Malformation Mimicking Recurrent Lymphoma on Dual Time-Point ¹⁸F-FDOPA PET

Although ¹⁸F-FDG is the dominant radiotracer for PET imaging of hematological malignancies, radiolabeled amino acids have also been investigated to improve image quality in areas of high ¹⁸F-FDG uptake such as the central nervous system. We present a case of a 57-year-old woman who underwent an ¹⁸F-FDOPA scan for primary CNS lymphoma, which demonstrated an unexpected false-positive uptake in the right frontal lobe, due to a developmental venous anomaly.