Abstract
Magnetic resonance imaging and magnetic resonance angiography (MRI/MRA) are widely used for evaluating the moyamoya disease (MMD). This study compared the diagnostic accuracy of 7 Tesla (T) and 3 T MRI/MRA in MMD. In this case control study, 12 patients [median age: 34 years; range (10–66 years)] with MMD and 12 healthy controls [median age: 25 years; range (22–59 years)] underwent both 7 T and 3 T MRI/MRA. To evaluate the accuracy of MRI/MRA in MMD, five criteria were compared between imaging systems of 7 T and 3 T: Suzuki grading system, internal carotid artery (ICA) diameter, ivy sign, flow void of the basal ganglia on T2-weighted images, and high signal intensity areas of the basal ganglia on time-of-flight (TOF) source images. No difference was observed between 7 T and 3 T MRI/MRA in Suzuki stage, ICA diameter, and ivy sign score; while, 7 T MRI/MRA showed a higher detection rate in the flow void on T2-weighted images and TOF source images (p < 0.001). Receiver operating characteristic curves of both T2 and TOF criteria showed that 7 T MRI/MRA had higher sensitivity and specificity than 3 T MRI/MRA. Our findings indicate that 7 T MRI/MRA is superior to 3 T MRI/MRA for the diagnosis of MMD in point of detecting the flow void in basal ganglia by T2-weighted and TOF images.
Original language | English |
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Pages (from-to) | 134-138 |
Number of pages | 5 |
Journal | Magnetic Resonance Imaging |
Volume | 37 |
DOIs | |
State | Published - 1 Apr 2017 |
Bibliographical note
Funding Information:The author acknowledge those who participants in this study. This work was supported by the National Research Foundation of Korea (NRF 2013R1A2A2A01067990 , NRF 2014K1A3A1A21001372 , NRF 2016H1D5A1908909 ). This work was supported in part by KBSI (Korea Basic Science Institute) grant # E35600 .
Publisher Copyright:
© 2016
Keywords
- 7 T
- Magnetic resonance angiography
- Magnetic resonance image
- Moyamoya disease