Comparison of 7 T and 3 T MRI in patients with moyamoya disease

Byeong Ho Oh, Hyeong Cheol Moon, Hyeon Man Baek, Youn Joo Lee, Sang Woo Kim, Young Jai Jeon, Gun Seok Lee, Hong Rae Kim, Jai Ho Choi, Kyung Soo Min, Mou Seop Lee, Young Gyu Kim, Dong Ho Kim, Won Seop Kim, Young Seok Park

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Magnetic resonance imaging and magnetic resonance angiography (MRI/MRA) are widely used for evaluating the moyamoya disease (MMD). This study compared the diagnostic accuracy of 7 Tesla (T) and 3 T MRI/MRA in MMD. In this case control study, 12 patients [median age: 34 years; range (10–66 years)] with MMD and 12 healthy controls [median age: 25 years; range (22–59 years)] underwent both 7 T and 3 T MRI/MRA. To evaluate the accuracy of MRI/MRA in MMD, five criteria were compared between imaging systems of 7 T and 3 T: Suzuki grading system, internal carotid artery (ICA) diameter, ivy sign, flow void of the basal ganglia on T2-weighted images, and high signal intensity areas of the basal ganglia on time-of-flight (TOF) source images. No difference was observed between 7 T and 3 T MRI/MRA in Suzuki stage, ICA diameter, and ivy sign score; while, 7 T MRI/MRA showed a higher detection rate in the flow void on T2-weighted images and TOF source images (p < 0.001). Receiver operating characteristic curves of both T2 and TOF criteria showed that 7 T MRI/MRA had higher sensitivity and specificity than 3 T MRI/MRA. Our findings indicate that 7 T MRI/MRA is superior to 3 T MRI/MRA for the diagnosis of MMD in point of detecting the flow void in basal ganglia by T2-weighted and TOF images.

Original languageEnglish
Pages (from-to)134-138
Number of pages5
JournalMagnetic Resonance Imaging
Volume37
DOIs
StatePublished - 1 Apr 2017

Bibliographical note

Funding Information:
The author acknowledge those who participants in this study. This work was supported by the National Research Foundation of Korea (NRF 2013R1A2A2A01067990 , NRF 2014K1A3A1A21001372 , NRF 2016H1D5A1908909 ). This work was supported in part by KBSI (Korea Basic Science Institute) grant # E35600 .

Publisher Copyright:
© 2016

Keywords

  • 7 T
  • Magnetic resonance angiography
  • Magnetic resonance image
  • Moyamoya disease

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