Comparison of clinical outcomes with three different aspheric intraocular lenses

Purpose: To compare the quality of vision achieved with different aspheric intraocular lens (IOL) implants. Methods: This prospective, comparative and randomized study included 90 eyes that underwent phacoemulsification and implantation with one of three different aspheric IOLs. Patients were assigned randomly to receive one type of aspheric IOL: Tecnis Z9003^ (Advanced Medical Optics, Santa Ana, California, USA) (Group A), Acrysof IQ SN60WF^ (Alcon Laboratories, Fort Worth, Texas, USA) (Group B) or Akreos ADAPT-AO^ (Bausch & Lomb, Rochester, New York, USA) (Group C). Ophthalmic examinations, including uncorrected visual acuity, best spectacle-corrected visual acuity (BCVA), refractive error, wavefront analysis, contrast sensitivity under mesopic and photopic conditions, and a subjective questionnaire, were performed postoperatively. Results: The mean BCVA, mean refractive error and high-order aberrations were not significantly different among the three groups. The spherical aberrations were 0.0021 ± 0.096 for group A, 0.048 ± 0.071 for group B and 0.11 ± 0.089 for group C, indicating a significantly lower magnitude in group A (p = 0.012). In addition, group A showed significantly better results in contrast sensitivity under mesopic (p = 0.042) and photopic (p = 0.047, 0.049) conditions at low spatial frequencies. Nevertheless, postoperative patient satisfaction was not different among the three groups. Conclusion: The Tecnis Z9003^ IOL reduced spherical aberrations and improved contrast sensitivity under mesopic and photopic conditions at low spatial frequencies. Nevertheless, the final visual quality was not different among the three groups.