Comparison of severity scoring systems of atopic dermatitis

Background: There are no serologic markers that accurately reflect the severity of atopic dermatitis (AD), many different scoring systems used in clinical practice and for research purposes have been developed for assessing the severity of AD. Objective: The goal of the present study was to evaluate the correlations between severity scoring systems of AD and clinical assessments of physicians and patients. Methods: We graded the severity of 418 AD patients, applying the SCORing of Atopic Dermtaitis (SCORAD), Objective SCORAD (oSCORAD), Eczema Area and Severity Index (EASI), Three Item Severity score, Rajka and Langeland score. Also, we evaluated the Physician's Global Assessment (PGA) and Visual Analog Scale (VAS) of pruritus and sleep loss. Results: here was significant positive correlation between oSCORAD and EASI and oSCORAD showed a good correlation with the other severity scoring systems. oSCORAD was highly correlated with PGA and VAS of pruritus and sleep loss. oSCORAD demonstrated the greatest correlation with body surface area, showing a linear relation. Conclusion: oSCORAD can assess the severity of AD with reflecting clinical assessments of physicians and patients and disease extent.