Composite liver tumors: a radiologic-pathologic correlation

Megha Nayyar; David K. Imagawa; Temel Tirkes; Aram N. Demirjian; Roozbeh Houshyar; Kumar Sandrasegaran; Chaitali S. Nangia; Tara Seery; P. Bhargava; Joon I.i. Choi; Chandana Lall

doi:10.3350/cmh.2014.20.4.406

Composite liver tumors: a radiologic-pathologic correlation

Megha Nayyar
, David K. Imagawa
, Temel Tirkes
, Aram N. Demirjian
, Roozbeh Houshyar
, Kumar Sandrasegaran
, Chaitali S. Nangia
, Tara Seery
, P. Bhargava
, Joon I.i. Choi
, Chandana Lall

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Bi-phenotypic neoplasm refers to tumors derived from a common cancer stem cell with unique capability to differentiate histologically into two distinct tumor types. Bi-phenotypic hepatocellular carcinoma-cholangiocarcinoma (HCC-CC), although a rare tumor, is important for clinicians to recognize, since treatment options targeting both elements of the tumor are crucial. Imaging findings of bi-phenotypic HCC-CC are not specific and include features of both HCC and CC. A combination of imaging and immuno-histochemical analysis is usually needed to make the diagnosis.

Original language	English
Pages (from-to)	406-410
Number of pages	5
Journal	Clinical and Molecular Hepatology
Volume	20
Issue number	4
DOIs	https://doi.org/10.3350/cmh.2014.20.4.406
State	Published - 1 Dec 2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Bi-phenotypic tumors
Cholangiocarcinoma
Computed tomography, Magnetic resonance imaging
Hepatoceullular carcinoma

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10.3350/cmh.2014.20.4.406

Cite this

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title = "Composite liver tumors: a radiologic-pathologic correlation",

abstract = "Bi-phenotypic neoplasm refers to tumors derived from a common cancer stem cell with unique capability to differentiate histologically into two distinct tumor types. Bi-phenotypic hepatocellular carcinoma-cholangiocarcinoma (HCC-CC), although a rare tumor, is important for clinicians to recognize, since treatment options targeting both elements of the tumor are crucial. Imaging findings of bi-phenotypic HCC-CC are not specific and include features of both HCC and CC. A combination of imaging and immuno-histochemical analysis is usually needed to make the diagnosis. ",

keywords = "Bi-phenotypic tumors, Cholangiocarcinoma, Computed tomography, Magnetic resonance imaging, Hepatoceullular carcinoma",

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doi = "10.3350/cmh.2014.20.4.406",

language = "English",

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TY - JOUR

T1 - Composite liver tumors

T2 - a radiologic-pathologic correlation

AU - Nayyar, Megha

AU - Imagawa, David K.

AU - Tirkes, Temel

AU - Demirjian, Aram N.

AU - Houshyar, Roozbeh

AU - Sandrasegaran, Kumar

AU - Nangia, Chaitali S.

AU - Seery, Tara

AU - Bhargava, P.

AU - Choi, Joon I.i.

AU - Lall, Chandana

PY - 2014/12/1

Y1 - 2014/12/1

N2 - Bi-phenotypic neoplasm refers to tumors derived from a common cancer stem cell with unique capability to differentiate histologically into two distinct tumor types. Bi-phenotypic hepatocellular carcinoma-cholangiocarcinoma (HCC-CC), although a rare tumor, is important for clinicians to recognize, since treatment options targeting both elements of the tumor are crucial. Imaging findings of bi-phenotypic HCC-CC are not specific and include features of both HCC and CC. A combination of imaging and immuno-histochemical analysis is usually needed to make the diagnosis.

AB - Bi-phenotypic neoplasm refers to tumors derived from a common cancer stem cell with unique capability to differentiate histologically into two distinct tumor types. Bi-phenotypic hepatocellular carcinoma-cholangiocarcinoma (HCC-CC), although a rare tumor, is important for clinicians to recognize, since treatment options targeting both elements of the tumor are crucial. Imaging findings of bi-phenotypic HCC-CC are not specific and include features of both HCC and CC. A combination of imaging and immuno-histochemical analysis is usually needed to make the diagnosis.

KW - Bi-phenotypic tumors

KW - Cholangiocarcinoma

KW - Computed tomography, Magnetic resonance imaging

KW - Hepatoceullular carcinoma

UR - https://www.scopus.com/pages/publications/84965094680

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DO - 10.3350/cmh.2014.20.4.406

M3 - Article

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AN - SCOPUS:84965094680

SN - 2287-2728

VL - 20

SP - 406

EP - 410

JO - Clinical and Molecular Hepatology

JF - Clinical and Molecular Hepatology

IS - 4

ER -

Composite liver tumors: a radiologic-pathologic correlation

Abstract

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Keywords

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