Conduction aphasia as an initial symptom in a patient with Creutzfeldt-Jakob disease

Ji Eun Song; Dong Won Yang; Hyun Jin Seo; Sam Yeol Ha; Kwang Yeol Park; Oh Sang Kwon; Young Chul Youn

doi:10.1016/j.jocn.2010.02.018

Conduction aphasia as an initial symptom in a patient with Creutzfeldt-Jakob disease

Ji Eun Song
, Dong Won Yang
, Hyun Jin Seo
, Sam Yeol Ha
, Kwang Yeol Park
, Oh Sang Kwon
, Young Chul Youn

Chung-Ang University

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

We report a 59-year-old woman who presented to our facility with conduction aphasia as an initial symptom which, within 3 months, was followed by generalized myoclonus and global aphasia. She had difficulty repeating words during the Korean-Western Aphasia Battery test. Diffusion-weighted MRI demonstrated ribbon-like hyperintensities in the bilateral temporal, parietal and occipital cerebral cortex. An electroencephalogram showed periodic discharges over the bilateral hemispheres, while single photo emission CT revealed diminished perfusion. After a positive finding of the 14-3-3 protein in her cerebrospinal fluid, she was diagnosed as having probable sporadic Creutzfeldt-Jakob disease.

Original language	English
Pages (from-to)	1341-1343
Number of pages	3
Journal	Journal of Clinical Neuroscience
Volume	17
Issue number	10
DOIs	https://doi.org/10.1016/j.jocn.2010.02.018
State	Published - Oct 2010

Bibliographical note

Funding Information:
This study was supported by a grant of the Korea Health 21 R&D Project, Ministry of Health & Welfare, Republic of Korea (A050079).

Keywords

Brain images
Conduction aphasia
Sporadic Creutzfeldt-Jakob disease

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10.1016/j.jocn.2010.02.018

Cite this

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title = "Conduction aphasia as an initial symptom in a patient with Creutzfeldt-Jakob disease",

abstract = "We report a 59-year-old woman who presented to our facility with conduction aphasia as an initial symptom which, within 3 months, was followed by generalized myoclonus and global aphasia. She had difficulty repeating words during the Korean-Western Aphasia Battery test. Diffusion-weighted MRI demonstrated ribbon-like hyperintensities in the bilateral temporal, parietal and occipital cerebral cortex. An electroencephalogram showed periodic discharges over the bilateral hemispheres, while single photo emission CT revealed diminished perfusion. After a positive finding of the 14-3-3 protein in her cerebrospinal fluid, she was diagnosed as having probable sporadic Creutzfeldt-Jakob disease.",

keywords = "Brain images, Conduction aphasia, Sporadic Creutzfeldt-Jakob disease",

author = "Song, \{Ji Eun\} and Yang, \{Dong Won\} and Seo, \{Hyun Jin\} and Ha, \{Sam Yeol\} and Park, \{Kwang Yeol\} and Kwon, \{Oh Sang\} and Youn, \{Young Chul\}",

note = "Funding Information: This study was supported by a grant of the Korea Health 21 R\&D Project, Ministry of Health \& Welfare, Republic of Korea (A050079).",

year = "2010",

month = oct,

doi = "10.1016/j.jocn.2010.02.018",

language = "English",

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pages = "1341--1343",

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AU - Song, Ji Eun

AU - Yang, Dong Won

AU - Seo, Hyun Jin

AU - Ha, Sam Yeol

AU - Park, Kwang Yeol

AU - Kwon, Oh Sang

AU - Youn, Young Chul

N1 - Funding Information: This study was supported by a grant of the Korea Health 21 R&D Project, Ministry of Health & Welfare, Republic of Korea (A050079).

PY - 2010/10

Y1 - 2010/10

N2 - We report a 59-year-old woman who presented to our facility with conduction aphasia as an initial symptom which, within 3 months, was followed by generalized myoclonus and global aphasia. She had difficulty repeating words during the Korean-Western Aphasia Battery test. Diffusion-weighted MRI demonstrated ribbon-like hyperintensities in the bilateral temporal, parietal and occipital cerebral cortex. An electroencephalogram showed periodic discharges over the bilateral hemispheres, while single photo emission CT revealed diminished perfusion. After a positive finding of the 14-3-3 protein in her cerebrospinal fluid, she was diagnosed as having probable sporadic Creutzfeldt-Jakob disease.

AB - We report a 59-year-old woman who presented to our facility with conduction aphasia as an initial symptom which, within 3 months, was followed by generalized myoclonus and global aphasia. She had difficulty repeating words during the Korean-Western Aphasia Battery test. Diffusion-weighted MRI demonstrated ribbon-like hyperintensities in the bilateral temporal, parietal and occipital cerebral cortex. An electroencephalogram showed periodic discharges over the bilateral hemispheres, while single photo emission CT revealed diminished perfusion. After a positive finding of the 14-3-3 protein in her cerebrospinal fluid, she was diagnosed as having probable sporadic Creutzfeldt-Jakob disease.

KW - Brain images

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KW - Sporadic Creutzfeldt-Jakob disease

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SN - 0967-5868

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JO - Journal of Clinical Neuroscience

JF - Journal of Clinical Neuroscience

IS - 10

ER -

Conduction aphasia as an initial symptom in a patient with Creutzfeldt-Jakob disease

Abstract

Bibliographical note

Keywords

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