Correction to: Treating Lower Urinary Tract Symptoms in Older Adults: Intravesical Options (Drugs & Aging, (2023), 40, 3, (241-261), 10.1007/s40266-023-01009-5)

In this article the caption to Figs. 2 and 3 were inadvertently swapped; the Figs. 2 and 3 should have appeared as shown below. (Figure presented.) (Figure presented.) Illustration of intravesical drug delivery via a transurethral catheter in female mice. Combined instillation of paramagnetic, gadolinium chelate, and superparamagnetic iron oxide nanoparticle with a polyglucose sorbitol carboxymethylether coating (ferumoxytol) by a catheter darkens the lumen but brightens the bladder wall. This occurs because the large molecular weight of ferumoxytol (731 kD, analogous to onabotulilinumtoxinA) exclusively spoils the gadolinium signal in the bladder lumen but not in the bladder wall and the larger molecular size of ferumoxytol restricts its diffusion to the bladder wall, whereas smaller sized gadolinium chelate (analogous to oxybutynin) can easily diffuse paracellularly into bladder wall. T₂-weighted images of mouse bladder acquired pre- and post-instillation of 0.05 mL (compared to 50 mL for human bladder) of contrast mixture illustrate the dramatic improvement in image contrast with a darkened lumen and a brightened bladder wall. The parameters for Turbo spin echo T₂-weighted multi-slice imaging in coronal orientation at 7T were: repetition time 3000 ms, echo time 40 ms, echo train length = 8; field of view 4 × 4 cm², acquisition matrix 256 × 256, slice thickness 1 mm and interslice gap of 1 mm in 15 slices, number of excitations = 4, and pixel size of 0.156 mm. LUTS lower urinary tract symptoms Sustained intravesical delivery using thermosensitive hydrogel: A bladder photographs of an anaesthetized rat taken 24 h after instillation of a [poly(ethylene glycol)-poly[lactic acid-co-glycolic acid]-poly(ethylene glycol)] polymer liquid at room temperature (25 °C) transitions reversibly to a sticky semi-solid that resists washing away by urine at 37 °C. Abdominal incision was made to photograph the white gel resting on the mucosal surface of the posterior bladder wall. B, C Principle of sustained intravesical drug delivery is illustrated by the coating of India ink (Ci, Cii) on the mucosal surface of rat bladder following bladder instillation of India ink (proxy for oxybutynin or onabotulinumtoxin A) as a 10% dispersion in liquid poly(ethylene glycol)-poly[lactic acid-co-glycolic acid]-poly(ethylene glycol)] polymer because regular voiding of urine washes away plain India ink (without hydrogel) instilled into rat bladder as evident from the pictures of rat bladder viewed under visible and ultraviolet (UV) light (Bi, Bii). Higher absorbance of India ink in UV light causes India ink to appear darker in UV light and the coating of umbrella cell borders is revealed by examination under high magnification (D) The original article has been corrected.