Decreased striatal dopamine transporter binding in a patient with extrapontine myelinolysis

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    Abstract

    We describe the case of a 61-year-old woman who developed extrapontine myelinolysis (EPM) with parkinsonism. Decreased striatal dopamine transporter binding assessed by tropane and single photon emission computed tomography ([123I]IPT) SPECT) were observed in the patient, suggesting that osmotic injury causes the demyelination of nigrostriatal dopaminergic neurons and that such injury may be involved in the pathogenesis of EPM with parkinsonism.

    Original languageEnglish
    Pages (from-to)342-345
    Number of pages4
    JournalMovement Disorders
    Volume18
    Issue number3
    DOIs
    StatePublished - 1 Mar 2003

    Keywords

    • Extrapontine myelinolysis
    • IPTSPECT
    • Parkinsonism

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