Depigmented extramammary Paget's disease

Extramammary Paget's disease (EMPD) is a rare skin neoplasm most commonly involving apocrine gland-bearing regions including the anogenital area and axillae. Typically, EMPD presents as erythematous plaque, usually well demarcated, and may demonstrate crusting, erosion and ulcerations. We herein report a patient with a depigmented patch as the sole sign of EMPD. Depigmented EMPD can be misdiagnosed as vitiligo or postinflammatory hypopigmentation. Depigmented EMPD should be considered in the differential diagnosis of hypopigmented lesions in the anogenital area.