Early neuropsychological detection and the characteristics of Parkinson's disease associated with mild dementia

In Uk Song; Joong Seok Kim; Du Shin Jeong; Hyun Joo Song; Kwang Soo Lee

doi:10.1016/j.parkreldis.2008.01.007

Early neuropsychological detection and the characteristics of Parkinson's disease associated with mild dementia

In Uk Song
, Joong Seok Kim
, Du Shin Jeong
, Hyun Joo Song
, Kwang Soo Lee

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Parkinson's disease (PD) may exhibit patterns of cognitive deficits, yet physicians are currently lacking operational criteria to define the clinical boundaries between PD and PD dementia (PDD). Therefore, we investigated the characteristics of the cognitive impairments in mild PDD. We recruited 30 PDD, 20 PD-MCI (PD with mild cognitive impairment without dementia) and 33 controls. All subjects were evaluated with detailed neuropsychological tests. Our results showed that visual memory, visuospatial functions, naming and calculation displayed more marked impairment than that of the other domains. Thus we suggest that adding cognitive dysfunctions of cortical type to the early cognitive deficits of PD-MCI can help predict the development of dementia.

Original language	English
Pages (from-to)	558-562
Number of pages	5
Journal	Parkinsonism and Related Disorders
Volume	14
Issue number	7
DOIs	https://doi.org/10.1016/j.parkreldis.2008.01.007
State	Published - Nov 2008

Keywords

Cognitive impairment
Mild Parkinson's disease dementia
Parkinson's disease

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10.1016/j.parkreldis.2008.01.007

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title = "Early neuropsychological detection and the characteristics of Parkinson's disease associated with mild dementia",

abstract = "Parkinson's disease (PD) may exhibit patterns of cognitive deficits, yet physicians are currently lacking operational criteria to define the clinical boundaries between PD and PD dementia (PDD). Therefore, we investigated the characteristics of the cognitive impairments in mild PDD. We recruited 30 PDD, 20 PD-MCI (PD with mild cognitive impairment without dementia) and 33 controls. All subjects were evaluated with detailed neuropsychological tests. Our results showed that visual memory, visuospatial functions, naming and calculation displayed more marked impairment than that of the other domains. Thus we suggest that adding cognitive dysfunctions of cortical type to the early cognitive deficits of PD-MCI can help predict the development of dementia.",

keywords = "Cognitive impairment, Mild Parkinson's disease dementia, Parkinson's disease",

author = "Song, \{In Uk\} and Kim, \{Joong Seok\} and Jeong, \{Du Shin\} and Song, \{Hyun Joo\} and Lee, \{Kwang Soo\}",

year = "2008",

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T1 - Early neuropsychological detection and the characteristics of Parkinson's disease associated with mild dementia

AU - Song, In Uk

AU - Kim, Joong Seok

AU - Jeong, Du Shin

AU - Song, Hyun Joo

AU - Lee, Kwang Soo

PY - 2008/11

Y1 - 2008/11

N2 - Parkinson's disease (PD) may exhibit patterns of cognitive deficits, yet physicians are currently lacking operational criteria to define the clinical boundaries between PD and PD dementia (PDD). Therefore, we investigated the characteristics of the cognitive impairments in mild PDD. We recruited 30 PDD, 20 PD-MCI (PD with mild cognitive impairment without dementia) and 33 controls. All subjects were evaluated with detailed neuropsychological tests. Our results showed that visual memory, visuospatial functions, naming and calculation displayed more marked impairment than that of the other domains. Thus we suggest that adding cognitive dysfunctions of cortical type to the early cognitive deficits of PD-MCI can help predict the development of dementia.

AB - Parkinson's disease (PD) may exhibit patterns of cognitive deficits, yet physicians are currently lacking operational criteria to define the clinical boundaries between PD and PD dementia (PDD). Therefore, we investigated the characteristics of the cognitive impairments in mild PDD. We recruited 30 PDD, 20 PD-MCI (PD with mild cognitive impairment without dementia) and 33 controls. All subjects were evaluated with detailed neuropsychological tests. Our results showed that visual memory, visuospatial functions, naming and calculation displayed more marked impairment than that of the other domains. Thus we suggest that adding cognitive dysfunctions of cortical type to the early cognitive deficits of PD-MCI can help predict the development of dementia.

KW - Cognitive impairment

KW - Mild Parkinson's disease dementia

KW - Parkinson's disease

UR - https://www.scopus.com/pages/publications/53749095078

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AN - SCOPUS:53749095078

SN - 1353-8020

VL - 14

SP - 558

EP - 562

JO - Parkinsonism and Related Disorders

JF - Parkinsonism and Related Disorders

IS - 7

ER -

Early neuropsychological detection and the characteristics of Parkinson's disease associated with mild dementia

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