EBV-associated haemophagocytic syndrome in a patient with Behçet's disease

S. H. Lee; S. D. Kim; S. H. Kim; H. R. Kim; E. J. Oh; C. H. Yoon; S. H. Lee; H. Y. Kim; Sung Hwan Park

doi:10.1080/03009740510015186

EBV-associated haemophagocytic syndrome in a patient with Behçet's disease

S. H. Lee
, S. D. Kim
, S. H. Kim
, H. R. Kim
, E. J. Oh
, C. H. Yoon
, S. H. Lee
, H. Y. Kim
, Sung Hwan Park

Catholic Univ. of Korea Coll. Med.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

We present a case of Epstein-Barr virus (EBV)-associated haemophagocytic syndrome in a patient with Behçet's disease. A 43-year-old man, who had been receiving treatment under the diagnosis of Behçet's disease for recurrent oral ulcers, genital ulcer, ileal ulcer, and arthritis, had been admitted for fever, headache, and nausea developed 3 days ago. Laboratory data showed pancytopaenia, an increase in liver enzymes, lactate dehydrogenase (LDH) and ferritin. Haemophagocytic syndrome was diagnosed from histiocytosis and haemophagocytosis by macrophages, shown in the bone marrow aspiration and biopsy, and in situ hybridization for EBV showed a positive finding. The patient recovered rapidly after steroid therapy. This is the first report of EBV-associated haemophagocytic syndrome developed in a patient with Behçet's disease.

Original language	English
Pages (from-to)	320-323
Number of pages	4
Journal	Scandinavian Journal of Rheumatology
Volume	34
Issue number	4
DOIs	https://doi.org/10.1080/03009740510015186
State	Published - 2005

Bibliographical note

Funding Information:
This work was supported by a grant from the Catholic Research Institute of Medical Science and a grant (R11-2002-098-0000-0) from KOSEF through the Rheumatism Research Centre at the Catholic University.

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10.1080/03009740510015186

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title = "EBV-associated haemophagocytic syndrome in a patient with Beh{\c c}et's disease",

abstract = "We present a case of Epstein-Barr virus (EBV)-associated haemophagocytic syndrome in a patient with Beh{\c c}et's disease. A 43-year-old man, who had been receiving treatment under the diagnosis of Beh{\c c}et's disease for recurrent oral ulcers, genital ulcer, ileal ulcer, and arthritis, had been admitted for fever, headache, and nausea developed 3 days ago. Laboratory data showed pancytopaenia, an increase in liver enzymes, lactate dehydrogenase (LDH) and ferritin. Haemophagocytic syndrome was diagnosed from histiocytosis and haemophagocytosis by macrophages, shown in the bone marrow aspiration and biopsy, and in situ hybridization for EBV showed a positive finding. The patient recovered rapidly after steroid therapy. This is the first report of EBV-associated haemophagocytic syndrome developed in a patient with Beh{\c c}et's disease.",

author = "Lee, \{S. H.\} and Kim, \{S. D.\} and Kim, \{S. H.\} and Kim, \{H. R.\} and Oh, \{E. J.\} and Yoon, \{C. H.\} and Lee, \{S. H.\} and Kim, \{H. Y.\} and Park, \{Sung Hwan\}",

note = "Funding Information: This work was supported by a grant from the Catholic Research Institute of Medical Science and a grant (R11-2002-098-0000-0) from KOSEF through the Rheumatism Research Centre at the Catholic University.",

year = "2005",

doi = "10.1080/03009740510015186",

language = "English",

volume = "34",

pages = "320--323",

journal = "Scandinavian Journal of Rheumatology",

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TY - JOUR

T1 - EBV-associated haemophagocytic syndrome in a patient with Behçet's disease

AU - Lee, S. H.

AU - Kim, S. D.

AU - Kim, S. H.

AU - Kim, H. R.

AU - Oh, E. J.

AU - Yoon, C. H.

AU - Lee, S. H.

AU - Kim, H. Y.

AU - Park, Sung Hwan

N1 - Funding Information: This work was supported by a grant from the Catholic Research Institute of Medical Science and a grant (R11-2002-098-0000-0) from KOSEF through the Rheumatism Research Centre at the Catholic University.

PY - 2005

Y1 - 2005

N2 - We present a case of Epstein-Barr virus (EBV)-associated haemophagocytic syndrome in a patient with Behçet's disease. A 43-year-old man, who had been receiving treatment under the diagnosis of Behçet's disease for recurrent oral ulcers, genital ulcer, ileal ulcer, and arthritis, had been admitted for fever, headache, and nausea developed 3 days ago. Laboratory data showed pancytopaenia, an increase in liver enzymes, lactate dehydrogenase (LDH) and ferritin. Haemophagocytic syndrome was diagnosed from histiocytosis and haemophagocytosis by macrophages, shown in the bone marrow aspiration and biopsy, and in situ hybridization for EBV showed a positive finding. The patient recovered rapidly after steroid therapy. This is the first report of EBV-associated haemophagocytic syndrome developed in a patient with Behçet's disease.

AB - We present a case of Epstein-Barr virus (EBV)-associated haemophagocytic syndrome in a patient with Behçet's disease. A 43-year-old man, who had been receiving treatment under the diagnosis of Behçet's disease for recurrent oral ulcers, genital ulcer, ileal ulcer, and arthritis, had been admitted for fever, headache, and nausea developed 3 days ago. Laboratory data showed pancytopaenia, an increase in liver enzymes, lactate dehydrogenase (LDH) and ferritin. Haemophagocytic syndrome was diagnosed from histiocytosis and haemophagocytosis by macrophages, shown in the bone marrow aspiration and biopsy, and in situ hybridization for EBV showed a positive finding. The patient recovered rapidly after steroid therapy. This is the first report of EBV-associated haemophagocytic syndrome developed in a patient with Behçet's disease.

UR - https://www.scopus.com/pages/publications/24044526867

U2 - 10.1080/03009740510015186

DO - 10.1080/03009740510015186

M3 - Article

C2 - 16195167

AN - SCOPUS:24044526867

SN - 0300-9742

VL - 34

SP - 320

EP - 323

JO - Scandinavian Journal of Rheumatology

JF - Scandinavian Journal of Rheumatology

IS - 4

ER -

EBV-associated haemophagocytic syndrome in a patient with Behçet's disease

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