Effect of three-dimensional scaffold geometry on chondrocyte adhesion

This paper compares the characteristics of chondrocyte adhesion on two types of three-dimensional (3-D) scaffold: types A and B. These 3-D scaffolds can be repeatedly constructed with the same dimensions using microstereolithography, a system that allows the fabrication of predesigned internal structures, such as pore size and porosity, by stacking the photopolymerized material. In tissue engineering, chondrocyte adhesion to a scaffold should have a major effect on the regeneration of cartilage. In this regard, we evaluated chondrocyte adhesion to two types of scaffold and found that chondrocyte adhesion was better on the type B scaffold than on the type A, demonstrating the importance of scaffold geometry in chondrocyte adhesion.