Elevated interleukin-10 levels in patients with ocular toxoplasmosis

Gee Hyun Kim; Jae Hyuck Kwak; Young Hoon Park

doi:10.3347/PHD.22172

Elevated interleukin-10 levels in patients with ocular toxoplasmosis

Gee Hyun Kim, Jae Hyuck Kwak, Young Hoon Park

Department of Ophthalmology

Catholic Univ. of Korea Coll. Med.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

In elderly patients, ocular toxoplasmosis is one of the most common etiologies of uveitis, which should be differentially diagnosed from ocular lymphoma, another common pathology of uveitis in older adults. The high level of interleukin (IL)-10 and an IL-10/IL-6 ratio higher than 1 (>1.0) are helpful parameters to diagnose ocular lymphoma. In this study, we used aqueous humor samples to detect 4 cases of ocular toxoplasmosis in patients with high levels of IL-10 and an IL-10/IL-6 ratio higher than 1. Our results show that ocular toxoplasmosis may be associated with increased cytokine levels in aqueous humor.

Original language	English
Pages (from-to)	310-316
Number of pages	7
Journal	Parasites, Hosts and Diseases
Volume	61
Issue number	3
DOIs	https://doi.org/10.3347/PHD.22172
State	Published - 1 Aug 2023

Keywords

cytokines
Interleukin-10
intraocular lymphoma
ocular toxoplasmosis
Toxoplasma gondii
uveitis

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10.3347/PHD.22172

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title = "Elevated interleukin-10 levels in patients with ocular toxoplasmosis",

abstract = "In elderly patients, ocular toxoplasmosis is one of the most common etiologies of uveitis, which should be differentially diagnosed from ocular lymphoma, another common pathology of uveitis in older adults. The high level of interleukin (IL)-10 and an IL-10/IL-6 ratio higher than 1 (>1.0) are helpful parameters to diagnose ocular lymphoma. In this study, we used aqueous humor samples to detect 4 cases of ocular toxoplasmosis in patients with high levels of IL-10 and an IL-10/IL-6 ratio higher than 1. Our results show that ocular toxoplasmosis may be associated with increased cytokine levels in aqueous humor.",

keywords = "cytokines, Interleukin-10, intraocular lymphoma, ocular toxoplasmosis, Toxoplasma gondii, uveitis",

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N2 - In elderly patients, ocular toxoplasmosis is one of the most common etiologies of uveitis, which should be differentially diagnosed from ocular lymphoma, another common pathology of uveitis in older adults. The high level of interleukin (IL)-10 and an IL-10/IL-6 ratio higher than 1 (>1.0) are helpful parameters to diagnose ocular lymphoma. In this study, we used aqueous humor samples to detect 4 cases of ocular toxoplasmosis in patients with high levels of IL-10 and an IL-10/IL-6 ratio higher than 1. Our results show that ocular toxoplasmosis may be associated with increased cytokine levels in aqueous humor.

AB - In elderly patients, ocular toxoplasmosis is one of the most common etiologies of uveitis, which should be differentially diagnosed from ocular lymphoma, another common pathology of uveitis in older adults. The high level of interleukin (IL)-10 and an IL-10/IL-6 ratio higher than 1 (>1.0) are helpful parameters to diagnose ocular lymphoma. In this study, we used aqueous humor samples to detect 4 cases of ocular toxoplasmosis in patients with high levels of IL-10 and an IL-10/IL-6 ratio higher than 1. Our results show that ocular toxoplasmosis may be associated with increased cytokine levels in aqueous humor.

KW - cytokines

KW - Interleukin-10

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KW - Toxoplasma gondii

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JO - Parasites, Hosts and Diseases

JF - Parasites, Hosts and Diseases

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ER -

Elevated interleukin-10 levels in patients with ocular toxoplasmosis

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Keywords

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