Extranasal T/NK-cell lymphoma presenting as intestinal diverticulum

Youn Soo Lee; Chang Suk Kang; Byung Kee Kim; Sang In Shim

doi:10.3346/jkms.2000.15.2.229

Extranasal T/NK-cell lymphoma presenting as intestinal diverticulum

Youn Soo Lee, Chang Suk Kang, Byung Kee Kim, Sang In Shim

The Catholic University of Korea

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

A case of intestinal angiocentric T/NK-cell lymphoma in a 58-year-old man is reported. The patient presented initially with panperitonitis because of perforation of sigmoid colon diverticulum. He underwent segmentectomy of involved bowel. Histologically, the intestinal wall showed diffuse infiltration of medium or large size lymphoma cells with angiocentric growth and necrosis. The lymphoma cells were CD56+, CD45RO, CD3+, CD4-, CD8-, CD20-, and CD30- in paraffin sections with germline configuration of TCR-γ gene, consistent with T/NK-cell lymphoma. Further staging revealed splenomegaly. Intestinal angiocentric T/NK cell lymphoma represents a distinct etiology of diverticulum with perforation.

Original language	English
Pages (from-to)	229-232
Number of pages	4
Journal	Journal of Korean Medical Science
Volume	15
Issue number	2
DOIs	https://doi.org/10.3346/jkms.2000.15.2.229
State	Published - Apr 2000

Keywords

Diverticulum
Gastrointestinal Neoplasms
Lymphoma, T/NK-Cell
Neoplasms, Sigmoid

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10.3346/jkms.2000.15.2.229

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title = "Extranasal T/NK-cell lymphoma presenting as intestinal diverticulum",

abstract = "A case of intestinal angiocentric T/NK-cell lymphoma in a 58-year-old man is reported. The patient presented initially with panperitonitis because of perforation of sigmoid colon diverticulum. He underwent segmentectomy of involved bowel. Histologically, the intestinal wall showed diffuse infiltration of medium or large size lymphoma cells with angiocentric growth and necrosis. The lymphoma cells were CD56+, CD45RO, CD3+, CD4-, CD8-, CD20-, and CD30- in paraffin sections with germline configuration of TCR-γ gene, consistent with T/NK-cell lymphoma. Further staging revealed splenomegaly. Intestinal angiocentric T/NK cell lymphoma represents a distinct etiology of diverticulum with perforation.",

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AU - Lee, Youn Soo

AU - Kang, Chang Suk

AU - Kim, Byung Kee

AU - Shim, Sang In

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N2 - A case of intestinal angiocentric T/NK-cell lymphoma in a 58-year-old man is reported. The patient presented initially with panperitonitis because of perforation of sigmoid colon diverticulum. He underwent segmentectomy of involved bowel. Histologically, the intestinal wall showed diffuse infiltration of medium or large size lymphoma cells with angiocentric growth and necrosis. The lymphoma cells were CD56+, CD45RO, CD3+, CD4-, CD8-, CD20-, and CD30- in paraffin sections with germline configuration of TCR-γ gene, consistent with T/NK-cell lymphoma. Further staging revealed splenomegaly. Intestinal angiocentric T/NK cell lymphoma represents a distinct etiology of diverticulum with perforation.

AB - A case of intestinal angiocentric T/NK-cell lymphoma in a 58-year-old man is reported. The patient presented initially with panperitonitis because of perforation of sigmoid colon diverticulum. He underwent segmentectomy of involved bowel. Histologically, the intestinal wall showed diffuse infiltration of medium or large size lymphoma cells with angiocentric growth and necrosis. The lymphoma cells were CD56+, CD45RO, CD3+, CD4-, CD8-, CD20-, and CD30- in paraffin sections with germline configuration of TCR-γ gene, consistent with T/NK-cell lymphoma. Further staging revealed splenomegaly. Intestinal angiocentric T/NK cell lymphoma represents a distinct etiology of diverticulum with perforation.

KW - Diverticulum

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KW - Lymphoma, T/NK-Cell

KW - Neoplasms, Sigmoid

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Extranasal T/NK-cell lymphoma presenting as intestinal diverticulum

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Keywords

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