Abstract
This manuscript reports on the fabrication of starch-lauric acid (St-LA) nanoparticles having potential cancer therapy. St-LA nanoparticles were fabricated by varying the amount of LA, and the optimized St-LA nanoparticles were found. In addition, it was confirmed that the St-LA nanoparticles were successfully fabricated through scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) analysis. In vitro, the St-LA nanoparticles showed cytotoxicity in A549 and Caco-2 cells but not NIH/3T3 cells. These results were confirmed by LIVE/DEAD staining and fluorescence imaging. Our next goal is to evaluate the St-LA nanoparticles containing various anticancer drugs through in vitro and in vivo studies. St-LA nanoparticles can potentially be applied to cancer chemotherapy.
| Original language | English |
|---|---|
| Pages (from-to) | 62-67 |
| Number of pages | 6 |
| Journal | Polymer (Korea) |
| Volume | 45 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2021 |
Bibliographical note
Publisher Copyright:©2021 The Polymer Society of Korea. All rights reserved.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Antitumor effect
- Lauric acid
- Nanoparticles
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