Five-year Progress of Gastric MALT Lymphoma Presenting as Gastric Outlet Obstruction

Hyundam Gu, Dae Young Cheung, Yeon Joo Seo, Eunjung Lee, Han Hee Lee, Jin Il Kim, Soo Heon Park, Tae Jung Kim

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

This paper reports a 70-year-old female with gastric extranodal marginal zone B cell lymphoma of mucosa-associated lymphoid tissue (gastric MALT lymphoma) as a rare case of gastric outlet obstruction. Five years earlier, she initially presented with weight loss and anemia. Esophagogastroduodenoscopy (EGD) revealed multiple gastric and duodenal ulcers with a pyloric deformity, while histology revealed chronic active inflammation and a Helicobacter pylori (H. pylori) infection. Three years earlier, she underwent EGD per the National Cancer Screening Program and was diagnosed with antral and duodenal ulcers. A forceps biopsy specimen from one of the ulcers showed the findings of gastric MALT lymphoma, but she did not visit the hospital for proper management. She visited complaining of a loss of appetite. EGD revealed a gastric outlet obstruction (GOO) caused by antral deformity and pyloric narrowing. A staged workup with CT and PET revealed full-layered, encircling antral wall thickening and several enlarged mesenteric lymph nodes. She was finally diagnosed with a gastric MALT lymphoma at Ann Arbor stage I1E with translocation t(11;18). She was treated with palliative surgery for GOO and systemic chemotherapy with a CHOP regimen. This paper reports a gastric MALT lymphoma that progressed from superficial mucosal lesions to an overt mass with regional lymph node metastasis for five years.

Original languageEnglish
Pages (from-to)265-269
Number of pages5
JournalThe Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
Volume81
Issue number6
DOIs
StatePublished - 25 Jun 2023

Keywords

  • Gastric outlet obstruction
  • MALT lymphoma
  • Stomach

Fingerprint

Dive into the research topics of 'Five-year Progress of Gastric MALT Lymphoma Presenting as Gastric Outlet Obstruction'. Together they form a unique fingerprint.

Cite this