Human fas associated factor 1, hFAF1, gene maps to chromosome band 1p32

Seung Wook Ryu; Hae Suk Kim; Sungjoo Kim Yoon; V. V.V.S. Murty; Eunhee Kim

doi:10.1007/s10059-000-0598-z

Human fas associated factor 1, hFAF1, gene maps to chromosome band 1p32

Seung Wook Ryu
, Hae Suk Kim
, Sungjoo Kim Yoon
, V. V.V.S. Murty
, Eunhee Kim

Department of Biomedicine & Health Science

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Human Fas associated factor 1 protein (hFAF1) is involved in the positive regulation of Fas signaling even though it can not initiate the signal for itself. By chromosomal assignment using somatic cell hybrids (CASH), the hFAF1 gene was located on human chromosome 1 between markers D1S443 and D1S197. The hFAF1 gene was mapped to human chromosome band 1p32 by FISH utilizing a genomic PAC clone containing the gene. In genomic Southern analysis using hFAF1 cDNA as a probe, several bands appeared in three different restriction enzyme digestions. The single band appearance in FISH analysis compared to several bands in Southern blots implies that the hFAF1 gene would be rather big or that an additional hFAF1 gene isotype(s) might be present in close vicinity.

Original language	English
Pages (from-to)	598-600
Number of pages	3
Journal	Molecules and Cells
Volume	10
Issue number	5
DOIs	https://doi.org/10.1007/s10059-000-0598-z
State	Published - 31 Oct 2000

Bibliographical note

Funding Information:
Acknowledgments This work was supported financially by the Korean Ministry of Science and Technology and by the Korea Science and Engineering Foundation through the Research Center for Biomedical Resources in PaiChai University, Korea.

Keywords

1p32
Chromosome
FAF1
Mapping

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@article{155fbfd97521466e8464111e918c58e9,

title = "Human fas associated factor 1, hFAF1, gene maps to chromosome band 1p32",

abstract = "Human Fas associated factor 1 protein (hFAF1) is involved in the positive regulation of Fas signaling even though it can not initiate the signal for itself. By chromosomal assignment using somatic cell hybrids (CASH), the hFAF1 gene was located on human chromosome 1 between markers D1S443 and D1S197. The hFAF1 gene was mapped to human chromosome band 1p32 by FISH utilizing a genomic PAC clone containing the gene. In genomic Southern analysis using hFAF1 cDNA as a probe, several bands appeared in three different restriction enzyme digestions. The single band appearance in FISH analysis compared to several bands in Southern blots implies that the hFAF1 gene would be rather big or that an additional hFAF1 gene isotype(s) might be present in close vicinity.",

keywords = "1p32, Chromosome, FAF1, Mapping",

author = "Ryu, \{Seung Wook\} and Kim, \{Hae Suk\} and Yoon, \{Sungjoo Kim\} and Murty, \{V. V.V.S.\} and Eunhee Kim",

note = "Funding Information: Acknowledgments This work was supported financially by the Korean Ministry of Science and Technology and by the Korea Science and Engineering Foundation through the Research Center for Biomedical Resources in PaiChai University, Korea.",

year = "2000",

month = oct,

day = "31",

doi = "10.1007/s10059-000-0598-z",

language = "English",

volume = "10",

pages = "598--600",

journal = "Molecules and Cells",

issn = "1016-8478",

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TY - JOUR

T1 - Human fas associated factor 1, hFAF1, gene maps to chromosome band 1p32

AU - Ryu, Seung Wook

AU - Kim, Hae Suk

AU - Yoon, Sungjoo Kim

AU - Murty, V. V.V.S.

AU - Kim, Eunhee

N1 - Funding Information: Acknowledgments This work was supported financially by the Korean Ministry of Science and Technology and by the Korea Science and Engineering Foundation through the Research Center for Biomedical Resources in PaiChai University, Korea.

PY - 2000/10/31

Y1 - 2000/10/31

N2 - Human Fas associated factor 1 protein (hFAF1) is involved in the positive regulation of Fas signaling even though it can not initiate the signal for itself. By chromosomal assignment using somatic cell hybrids (CASH), the hFAF1 gene was located on human chromosome 1 between markers D1S443 and D1S197. The hFAF1 gene was mapped to human chromosome band 1p32 by FISH utilizing a genomic PAC clone containing the gene. In genomic Southern analysis using hFAF1 cDNA as a probe, several bands appeared in three different restriction enzyme digestions. The single band appearance in FISH analysis compared to several bands in Southern blots implies that the hFAF1 gene would be rather big or that an additional hFAF1 gene isotype(s) might be present in close vicinity.

AB - Human Fas associated factor 1 protein (hFAF1) is involved in the positive regulation of Fas signaling even though it can not initiate the signal for itself. By chromosomal assignment using somatic cell hybrids (CASH), the hFAF1 gene was located on human chromosome 1 between markers D1S443 and D1S197. The hFAF1 gene was mapped to human chromosome band 1p32 by FISH utilizing a genomic PAC clone containing the gene. In genomic Southern analysis using hFAF1 cDNA as a probe, several bands appeared in three different restriction enzyme digestions. The single band appearance in FISH analysis compared to several bands in Southern blots implies that the hFAF1 gene would be rather big or that an additional hFAF1 gene isotype(s) might be present in close vicinity.

KW - 1p32

KW - Chromosome

KW - FAF1

KW - Mapping

UR - https://www.scopus.com/pages/publications/0034739489

U2 - 10.1007/s10059-000-0598-z

DO - 10.1007/s10059-000-0598-z

M3 - Article

C2 - 11101154

AN - SCOPUS:0034739489

SN - 1016-8478

VL - 10

SP - 598

EP - 600

JO - Molecules and Cells

JF - Molecules and Cells

IS - 5

ER -

Human fas associated factor 1, hFAF1, gene maps to chromosome band 1p32

Abstract

Bibliographical note

Keywords

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