Increased incidence of uterine leiomyoma in young females with depression: An observational study

Ahra Lee; Kyungdo Han; Soyeon Kang; Dongjin Kwon; Jeong Namkung; Minjeong Kim; Youn Jee Chung; Jaeyen Song; Joohee Yoon; Mee Ran Kim

doi:10.1016/j.isci.2024.110896

Increased incidence of uterine leiomyoma in young females with depression: An observational study

Ahra Lee
, Kyungdo Han
, Soyeon Kang
, Dongjin Kwon
, Jeong Namkung
, Minjeong Kim
, Youn Jee Chung
, Jaeyen Song
, Joohee Yoon
, Mee Ran Kim

Department of Obstetrics and Gynecology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Based on analyses of 22,487,947 person-years of follow-up data in a cohort of 2,523,565 young females, we found that the presence of depression was associated with a higher cumulative incidence of new-onset uterine leiomyoma than the absence of depression. This risk was even higher in patients with recurrent depression, and depression had a significant interaction with relatively old age and dyslipidemia. Screening for uterine leiomyoma is advisable in young females experiencing depression, as they appear to be at increased risk for developing this tumor type.

Original language	English
Article number	110896
Journal	iScience
Volume	27
Issue number	10
DOIs	https://doi.org/10.1016/j.isci.2024.110896
State	Published - 18 Oct 2024

Bibliographical note

Publisher Copyright:
© 2024 The Author(s)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Female reproductive endocrinology
Psychology
Public health

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10.1016/j.isci.2024.110896

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title = "Increased incidence of uterine leiomyoma in young females with depression: An observational study",

abstract = "Based on analyses of 22,487,947 person-years of follow-up data in a cohort of 2,523,565 young females, we found that the presence of depression was associated with a higher cumulative incidence of new-onset uterine leiomyoma than the absence of depression. This risk was even higher in patients with recurrent depression, and depression had a significant interaction with relatively old age and dyslipidemia. Screening for uterine leiomyoma is advisable in young females experiencing depression, as they appear to be at increased risk for developing this tumor type.",

keywords = "Female reproductive endocrinology, Psychology, Public health",

author = "Ahra Lee and Kyungdo Han and Soyeon Kang and Dongjin Kwon and Jeong Namkung and Minjeong Kim and Chung, \{Youn Jee\} and Jaeyen Song and Joohee Yoon and Kim, \{Mee Ran\}",

note = "Publisher Copyright: {\textcopyright} 2024 The Author(s)",

year = "2024",

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doi = "10.1016/j.isci.2024.110896",

language = "English",

volume = "27",

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T1 - Increased incidence of uterine leiomyoma in young females with depression

T2 - An observational study

AU - Lee, Ahra

AU - Han, Kyungdo

AU - Kang, Soyeon

AU - Kwon, Dongjin

AU - Namkung, Jeong

AU - Kim, Minjeong

AU - Chung, Youn Jee

AU - Song, Jaeyen

AU - Yoon, Joohee

AU - Kim, Mee Ran

PY - 2024/10/18

Y1 - 2024/10/18

N2 - Based on analyses of 22,487,947 person-years of follow-up data in a cohort of 2,523,565 young females, we found that the presence of depression was associated with a higher cumulative incidence of new-onset uterine leiomyoma than the absence of depression. This risk was even higher in patients with recurrent depression, and depression had a significant interaction with relatively old age and dyslipidemia. Screening for uterine leiomyoma is advisable in young females experiencing depression, as they appear to be at increased risk for developing this tumor type.

AB - Based on analyses of 22,487,947 person-years of follow-up data in a cohort of 2,523,565 young females, we found that the presence of depression was associated with a higher cumulative incidence of new-onset uterine leiomyoma than the absence of depression. This risk was even higher in patients with recurrent depression, and depression had a significant interaction with relatively old age and dyslipidemia. Screening for uterine leiomyoma is advisable in young females experiencing depression, as they appear to be at increased risk for developing this tumor type.

KW - Female reproductive endocrinology

KW - Psychology

KW - Public health

UR - https://www.scopus.com/pages/publications/85207756651

U2 - 10.1016/j.isci.2024.110896

DO - 10.1016/j.isci.2024.110896

M3 - Article

AN - SCOPUS:85207756651

SN - 2589-0042

VL - 27

JO - iScience

JF - iScience

IS - 10

M1 - 110896

ER -

Increased incidence of uterine leiomyoma in young females with depression: An observational study

Abstract

Bibliographical note

UN SDGs

Keywords

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