Keratinocytes cut corners on the cell cycle for the sake of skin barrier integrity

Renzhi Hou; Jung Eun Kim; Maksim V. Plikus

doi:10.1016/j.devcel.2022.06.001

Keratinocytes cut corners on the cell cycle for the sake of skin barrier integrity

Renzhi Hou
, Jung Eun Kim
, Maksim V. Plikus

Department of Dermatology

University of California at Irvine

Research output: Contribution to journal › Comment/debate

2 Scopus citations

Abstract

Epidermis can grow its surface by activating mitotic division in basal stem cells. In a recent issue of Nature, Chan et al. (2022) show that under high demand for new skin, differentiated epidermal cells in zebrafish divide without DNA synthesis, forming cells in the new surface with reduced and abnormal genomes.

Original language	English
Pages (from-to)	1437-1438
Number of pages	2
Journal	Developmental Cell
Volume	57
Issue number	12
DOIs	https://doi.org/10.1016/j.devcel.2022.06.001
State	Published - 20 Jun 2022

Bibliographical note

Publisher Copyright:
© 2022 Elsevier Inc.

Access to Document

10.1016/j.devcel.2022.06.001

Cite this

@article{63ddc94af7424dbeba659a411c66e1c7,

title = "Keratinocytes cut corners on the cell cycle for the sake of skin barrier integrity",

abstract = "Epidermis can grow its surface by activating mitotic division in basal stem cells. In a recent issue of Nature, Chan et al. (2022) show that under high demand for new skin, differentiated epidermal cells in zebrafish divide without DNA synthesis, forming cells in the new surface with reduced and abnormal genomes.",

author = "Renzhi Hou and Kim, \{Jung Eun\} and Plikus, \{Maksim V.\}",

note = "Publisher Copyright: {\textcopyright} 2022 Elsevier Inc.",

year = "2022",

month = jun,

day = "20",

doi = "10.1016/j.devcel.2022.06.001",

language = "English",

volume = "57",

pages = "1437--1438",

journal = "Developmental Cell",

issn = "1534-5807",

publisher = "Cell Press",

number = "12",

}

TY - JOUR

T1 - Keratinocytes cut corners on the cell cycle for the sake of skin barrier integrity

AU - Hou, Renzhi

AU - Kim, Jung Eun

AU - Plikus, Maksim V.

PY - 2022/6/20

Y1 - 2022/6/20

N2 - Epidermis can grow its surface by activating mitotic division in basal stem cells. In a recent issue of Nature, Chan et al. (2022) show that under high demand for new skin, differentiated epidermal cells in zebrafish divide without DNA synthesis, forming cells in the new surface with reduced and abnormal genomes.

AB - Epidermis can grow its surface by activating mitotic division in basal stem cells. In a recent issue of Nature, Chan et al. (2022) show that under high demand for new skin, differentiated epidermal cells in zebrafish divide without DNA synthesis, forming cells in the new surface with reduced and abnormal genomes.

UR - https://www.scopus.com/pages/publications/85132259371

U2 - 10.1016/j.devcel.2022.06.001

DO - 10.1016/j.devcel.2022.06.001

M3 - Comment/debate

C2 - 35728520

AN - SCOPUS:85132259371

SN - 1534-5807

VL - 57

SP - 1437

EP - 1438

JO - Developmental Cell

JF - Developmental Cell

IS - 12

ER -

Keratinocytes cut corners on the cell cycle for the sake of skin barrier integrity

Abstract

Bibliographical note

Access to Document

Other files and links

Fingerprint

Cite this