Abstract
The KOrean College of Rheumatology BIOlogics and targeted therapy (KOBIO) registry is a nationwide observational cohort that captures detailed data on exposure of patients to biologic and targeted synthetic disease-modifying anti-rheumatic drugs (DMARDs). This registry was launched in December 2012 with an aim to prospectively investigate clinical manifestations and outcomes of patients with rheumatoid arthritis (RA), ankylosing spondylitis, and psoriatic arthritis who initiated a biologic or targeted synthetic DMARD or switched to another. Demographic data, disease activity, current treatment, adverse events, terms based on Medical Dictionary for Regulatory Activities, and so on are registered for patients who are then followed up annually in a web-based unified platform. The KOBIO registry also recruits and collects data of patients with RA on conventional DMARDs for comparison. As of today, more than 5,500 patients were enrolled from 47 academic and community Rheumatology centers across Korea. The KOBIO registry has evolved to become a powerful database for clinical research to improve clinical outcomes and quality of treatment.
Original language | English |
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Pages (from-to) | 176-182 |
Number of pages | 7 |
Journal | Journal of Rheumatic Diseases |
Volume | 28 |
Issue number | 4 |
DOIs | |
State | Published - 2021 |
Bibliographical note
Funding Information:We would like to thank Kimmie Hyrich, Kath Watson, Ms. Kim HJ and the KCR administrative staff, current and previous members of the study team, INFOrang, Ltd., and the generous donation of biopharmaceutical companies that made KOBIO possible.
Publisher Copyright:
Copyright © 2021 by The Korean College of Rheumatology.
Keywords
- Ankylosing spondylitis
- Biological products
- Psoriatic arthritis
- Registries
- Rheumatoid arthritis