Limbic encephalitis manifesting as selective amnesia and seizure-like activity: A case report

So Yeon Kim; Yoo Hyun Um; Sung Chul Lim; Jong Hyun Jeong

doi:10.9758/cpn.2018.16.1.109

Limbic encephalitis manifesting as selective amnesia and seizure-like activity: A case report

So Yeon Kim
, Yoo Hyun Um
, Sung Chul Lim
, Jong Hyun Jeong

Department of Psychiatry

The Catholic University of Korea, St. Vincent's Hospital
The Catholic University of Korea

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Limbic encephalitis (LE) is characterized by short-term memory loss, disorientation, agitation, seizures, and histopathological evidence of medial temporal lobe inflammation. Leucine-rich, glioma inactivated 1 (LGI-1) is an auto-antigen associated with LE. We report a 37-year-old male patient with LGI-1-related LE who presented with recurrent episodes of selective amnesia, seizure-like activity, confusion, and personality change. His symptoms were significantly improved with steroid therapy. Thorough differential diagnosis with consideration for autoimmune encephalitis should be in patients with presentation of symptoms, such as memory impairment, personality change and seizure-like activity, especially when other neurological diagnoses are excluded.

Original language	English
Pages (from-to)	109-113
Number of pages	5
Journal	Clinical Psychopharmacology and Neuroscience
Volume	16
Issue number	1
DOIs	https://doi.org/10.9758/cpn.2018.16.1.109
State	Published - Feb 2018

Bibliographical note

Publisher Copyright:
Copyright © 2018, Korean College of Neuropsychopharmacology.

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Anti-LGI-1 antibody encephalitis
Neuropsychiatric symptoms
Steroid therapy

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10.9758/cpn.2018.16.1.109

Cite this

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title = "Limbic encephalitis manifesting as selective amnesia and seizure-like activity: A case report",

abstract = "Limbic encephalitis (LE) is characterized by short-term memory loss, disorientation, agitation, seizures, and histopathological evidence of medial temporal lobe inflammation. Leucine-rich, glioma inactivated 1 (LGI-1) is an auto-antigen associated with LE. We report a 37-year-old male patient with LGI-1-related LE who presented with recurrent episodes of selective amnesia, seizure-like activity, confusion, and personality change. His symptoms were significantly improved with steroid therapy. Thorough differential diagnosis with consideration for autoimmune encephalitis should be in patients with presentation of symptoms, such as memory impairment, personality change and seizure-like activity, especially when other neurological diagnoses are excluded.",

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author = "Kim, \{So Yeon\} and Um, \{Yoo Hyun\} and Lim, \{Sung Chul\} and Jeong, \{Jong Hyun\}",

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year = "2018",

month = feb,

doi = "10.9758/cpn.2018.16.1.109",

language = "English",

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T1 - Limbic encephalitis manifesting as selective amnesia and seizure-like activity

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AU - Jeong, Jong Hyun

PY - 2018/2

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N2 - Limbic encephalitis (LE) is characterized by short-term memory loss, disorientation, agitation, seizures, and histopathological evidence of medial temporal lobe inflammation. Leucine-rich, glioma inactivated 1 (LGI-1) is an auto-antigen associated with LE. We report a 37-year-old male patient with LGI-1-related LE who presented with recurrent episodes of selective amnesia, seizure-like activity, confusion, and personality change. His symptoms were significantly improved with steroid therapy. Thorough differential diagnosis with consideration for autoimmune encephalitis should be in patients with presentation of symptoms, such as memory impairment, personality change and seizure-like activity, especially when other neurological diagnoses are excluded.

AB - Limbic encephalitis (LE) is characterized by short-term memory loss, disorientation, agitation, seizures, and histopathological evidence of medial temporal lobe inflammation. Leucine-rich, glioma inactivated 1 (LGI-1) is an auto-antigen associated with LE. We report a 37-year-old male patient with LGI-1-related LE who presented with recurrent episodes of selective amnesia, seizure-like activity, confusion, and personality change. His symptoms were significantly improved with steroid therapy. Thorough differential diagnosis with consideration for autoimmune encephalitis should be in patients with presentation of symptoms, such as memory impairment, personality change and seizure-like activity, especially when other neurological diagnoses are excluded.

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KW - Neuropsychiatric symptoms

KW - Steroid therapy

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AN - SCOPUS:85041688526

SN - 1738-1088

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JO - Clinical Psychopharmacology and Neuroscience

JF - Clinical Psychopharmacology and Neuroscience

IS - 1

ER -

Limbic encephalitis manifesting as selective amnesia and seizure-like activity: A case report

Abstract

Bibliographical note

UN SDGs

Keywords

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