Abstract
In order to understand the molecular mechanisms of chemotaxes through reactive oxygen species(ROS), the polymeric chemoattractants with free radical generating compounds were prepared, and the migrational behavior of melanoma cells towards the samples was investigated using a Boyden chamber assay. The samples with quinoid compounds had an enhanced melanoma cells migration than control. The migrational abilities of cells were further increased when the free radicals on the surface of samples were activated with blood plasma.
| Original language | English |
|---|---|
| Pages (from-to) | 927-931 |
| Number of pages | 5 |
| Journal | Tissue Engineering and Regenerative Medicine |
| Volume | 5 |
| Issue number | 4-6 |
| State | Published - Dec 2008 |
Keywords
- Chemotaxis
- Free radicals
- Hydroquinone
- Melanoma
- Migration
- Vitamin K1
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