Molecular epidemiology and genetic diversity of human astrovirus in South Korea from 2002 to 2007

A. Y. Jeong; H. S. Jeong; M. Y. Jo; S. Y. Jung; M. S. Lee; J. S. Lee; Y. M. Jee; J. H. Kim; D. S. Cheon

doi:10.1111/j.1469-0691.2010.03263.x

Molecular epidemiology and genetic diversity of human astrovirus in South Korea from 2002 to 2007

A. Y. Jeong
, H. S. Jeong
, M. Y. Jo
, S. Y. Jung
, M. S. Lee
, J. S. Lee
, Y. M. Jee
, J. H. Kim
, D. S. Cheon

Department of Pediatrics

Korea National Institute of Health

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

The present study was conducted to survey the prevalence and genotypic distribution of human astrovirus (HAstV) circulating in South Korea. Of 160,027 patients with acute gastroenteritis, 2,057 (1.3%) were positive for HAstV antigen. We determined the genotypes of 187 HAstV strains collected from laboratories across the country. Genetic analysis revealed genotype 1 to be the most prevalent, accounting for 72.19% of the strains, followed by genotypes 8 (9.63%), 6 (6.95%), 4 (6.42%), 2 (3.21%) and 3 (1.60%). Our findings indicate that HAstV is less common but, even so, a potentially important viral agent of gastroenteritis in South Korea, with significant genetic diversity among circulating HAstV strains.

Original language	English
Pages (from-to)	404-408
Number of pages	5
Journal	Clinical Microbiology and Infection
Volume	17
Issue number	3
DOIs	https://doi.org/10.1111/j.1469-0691.2010.03263.x
State	Published - Mar 2011

Bibliographical note

Funding Information:
This study was supported by an intramural fund from the National Institute of Health (NIH-091–4851–300), Republic of Korea.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Astrovirus
Epidemiology
Gastroenteritis
Genotype

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10.1111/j.1469-0691.2010.03263.x

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title = "Molecular epidemiology and genetic diversity of human astrovirus in South Korea from 2002 to 2007",

abstract = "The present study was conducted to survey the prevalence and genotypic distribution of human astrovirus (HAstV) circulating in South Korea. Of 160,027 patients with acute gastroenteritis, 2,057 (1.3\%) were positive for HAstV antigen. We determined the genotypes of 187 HAstV strains collected from laboratories across the country. Genetic analysis revealed genotype 1 to be the most prevalent, accounting for 72.19\% of the strains, followed by genotypes 8 (9.63\%), 6 (6.95\%), 4 (6.42\%), 2 (3.21\%) and 3 (1.60\%). Our findings indicate that HAstV is less common but, even so, a potentially important viral agent of gastroenteritis in South Korea, with significant genetic diversity among circulating HAstV strains.",

keywords = "Astrovirus, Epidemiology, Gastroenteritis, Genotype",

author = "Jeong, \{A. Y.\} and Jeong, \{H. S.\} and Jo, \{M. Y.\} and Jung, \{S. Y.\} and Lee, \{M. S.\} and Lee, \{J. S.\} and Jee, \{Y. M.\} and Kim, \{J. H.\} and Cheon, \{D. S.\}",

note = "Funding Information: This study was supported by an intramural fund from the National Institute of Health (NIH-091–4851–300), Republic of Korea.",

year = "2011",

month = mar,

doi = "10.1111/j.1469-0691.2010.03263.x",

language = "English",

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pages = "404--408",

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AU - Jeong, A. Y.

AU - Jeong, H. S.

AU - Jo, M. Y.

AU - Jung, S. Y.

AU - Lee, M. S.

AU - Lee, J. S.

AU - Jee, Y. M.

AU - Kim, J. H.

AU - Cheon, D. S.

N1 - Funding Information: This study was supported by an intramural fund from the National Institute of Health (NIH-091–4851–300), Republic of Korea.

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N2 - The present study was conducted to survey the prevalence and genotypic distribution of human astrovirus (HAstV) circulating in South Korea. Of 160,027 patients with acute gastroenteritis, 2,057 (1.3%) were positive for HAstV antigen. We determined the genotypes of 187 HAstV strains collected from laboratories across the country. Genetic analysis revealed genotype 1 to be the most prevalent, accounting for 72.19% of the strains, followed by genotypes 8 (9.63%), 6 (6.95%), 4 (6.42%), 2 (3.21%) and 3 (1.60%). Our findings indicate that HAstV is less common but, even so, a potentially important viral agent of gastroenteritis in South Korea, with significant genetic diversity among circulating HAstV strains.

AB - The present study was conducted to survey the prevalence and genotypic distribution of human astrovirus (HAstV) circulating in South Korea. Of 160,027 patients with acute gastroenteritis, 2,057 (1.3%) were positive for HAstV antigen. We determined the genotypes of 187 HAstV strains collected from laboratories across the country. Genetic analysis revealed genotype 1 to be the most prevalent, accounting for 72.19% of the strains, followed by genotypes 8 (9.63%), 6 (6.95%), 4 (6.42%), 2 (3.21%) and 3 (1.60%). Our findings indicate that HAstV is less common but, even so, a potentially important viral agent of gastroenteritis in South Korea, with significant genetic diversity among circulating HAstV strains.

KW - Astrovirus

KW - Epidemiology

KW - Gastroenteritis

KW - Genotype

UR - https://www.scopus.com/pages/publications/79751520996

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M3 - Article

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SN - 1198-743X

VL - 17

SP - 404

EP - 408

JO - Clinical Microbiology and Infection

JF - Clinical Microbiology and Infection

IS - 3

ER -

Molecular epidemiology and genetic diversity of human astrovirus in South Korea from 2002 to 2007

Abstract

Bibliographical note

UN SDGs

Keywords

Access to Document

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