Monocyte chemoattractant protein-1 (MCP1) promoter -2518 polymorphism may confer a susceptibility to major depressive disorder in the Korean population

Chi Un Pae; Hye Sook Yu; Tae Suk Kim; Chang Uk Lee; Soo Jung Lee; Tae Youn Jun; Chul Lee; Alessandro Serretti; In Ho Paik

doi:10.1016/j.psychres.2004.04.004

Monocyte chemoattractant protein-1 (MCP1) promoter -2518 polymorphism may confer a susceptibility to major depressive disorder in the Korean population

Chi Un Pae
, Hye Sook Yu
, Tae Suk Kim
, Chang Uk Lee
, Soo Jung Lee
, Tae Youn Jun
, Chul Lee
, Alessandro Serretti
, In Ho Paik

Department of Psychiatry

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

We conducted a case-control association study of the monocyte chemoattractant protein-1 (MCP1) gene -2518 polymorphism in 90 patients with major depressive disorder. Genotyping was performed by polymerase chain reaction methods. We found significant differences in genotype and allele frequencies. The present study suggests that this polymorphism may confer a susceptibility to major depressive disorder in the Korean population.

Original language	English
Pages (from-to)	279-281
Number of pages	3
Journal	Psychiatry Research
Volume	127
Issue number	3
DOIs	https://doi.org/10.1016/j.psychres.2004.04.004
State	Published - 15 Jul 2004

Bibliographical note

Funding Information:
This study was supported by a grant of the Korea Health 21 R&D project (02-PJ1-PG3-20506-0001), Ministry of Health & Welfare, Republic of Korea.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

MCP1 gene -2518 polymorphism
Major depressive disorder

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10.1016/j.psychres.2004.04.004

Cite this

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title = "Monocyte chemoattractant protein-1 (MCP1) promoter -2518 polymorphism may confer a susceptibility to major depressive disorder in the Korean population",

abstract = "We conducted a case-control association study of the monocyte chemoattractant protein-1 (MCP1) gene -2518 polymorphism in 90 patients with major depressive disorder. Genotyping was performed by polymerase chain reaction methods. We found significant differences in genotype and allele frequencies. The present study suggests that this polymorphism may confer a susceptibility to major depressive disorder in the Korean population.",

keywords = "MCP1 gene -2518 polymorphism, Major depressive disorder",

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note = "Funding Information: This study was supported by a grant of the Korea Health 21 R\&D project (02-PJ1-PG3-20506-0001), Ministry of Health \& Welfare, Republic of Korea.",

year = "2004",

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doi = "10.1016/j.psychres.2004.04.004",

language = "English",

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journal = "Psychiatry Research",

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T1 - Monocyte chemoattractant protein-1 (MCP1) promoter -2518 polymorphism may confer a susceptibility to major depressive disorder in the Korean population

AU - Pae, Chi Un

AU - Yu, Hye Sook

AU - Kim, Tae Suk

AU - Lee, Chang Uk

AU - Lee, Soo Jung

AU - Jun, Tae Youn

AU - Lee, Chul

AU - Serretti, Alessandro

AU - Paik, In Ho

N1 - Funding Information: This study was supported by a grant of the Korea Health 21 R&D project (02-PJ1-PG3-20506-0001), Ministry of Health & Welfare, Republic of Korea.

PY - 2004/7/15

Y1 - 2004/7/15

N2 - We conducted a case-control association study of the monocyte chemoattractant protein-1 (MCP1) gene -2518 polymorphism in 90 patients with major depressive disorder. Genotyping was performed by polymerase chain reaction methods. We found significant differences in genotype and allele frequencies. The present study suggests that this polymorphism may confer a susceptibility to major depressive disorder in the Korean population.

AB - We conducted a case-control association study of the monocyte chemoattractant protein-1 (MCP1) gene -2518 polymorphism in 90 patients with major depressive disorder. Genotyping was performed by polymerase chain reaction methods. We found significant differences in genotype and allele frequencies. The present study suggests that this polymorphism may confer a susceptibility to major depressive disorder in the Korean population.

KW - MCP1 gene -2518 polymorphism

KW - Major depressive disorder

UR - https://www.scopus.com/pages/publications/3543067577

U2 - 10.1016/j.psychres.2004.04.004

DO - 10.1016/j.psychres.2004.04.004

M3 - Article

C2 - 15296827

AN - SCOPUS:3543067577

SN - 0165-1781

VL - 127

SP - 279

EP - 281

JO - Psychiatry Research

JF - Psychiatry Research

IS - 3

ER -

Monocyte chemoattractant protein-1 (MCP1) promoter -2518 polymorphism may confer a susceptibility to major depressive disorder in the Korean population

Abstract

Bibliographical note

UN SDGs

Keywords

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