New Potential Therapies for Chronic Hepatitis B

Sun Hong Yoo; Jung Hyun Kwon

doi:10.4166/kjg.2019.74.5.267

New Potential Therapies for Chronic Hepatitis B

Sun Hong Yoo
, Jung Hyun Kwon

Department of Internal Medicine

The Catholic University of Korea Incheon St. Mary's Hospital

Research output: Contribution to journal › Review article › peer-review

Abstract

A HBV infection is a dynamic disease and long-term liver inflammation contributes to the development of liver cirrhosis and hepatocellular carcinoma. Currently available nucleos(t)ide analogues and pegylated interferon are effective in inhibiting HBV replication but rarely achieve HBsAg clearance. The present article introduces a new definition of HBV cure and several emerging therapies for HBV cure, including direct acting antivirals and immune modulatory antivirals.

Original language	English
Pages (from-to)	267-273
Number of pages	7
Journal	The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
Volume	74
Issue number	5
DOIs	https://doi.org/10.4166/kjg.2019.74.5.267
State	Published - 25 Nov 2019

Keywords

Hepatitis B virus
Therapeutics

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.4166/kjg.2019.74.5.267

Cite this

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title = "New Potential Therapies for Chronic Hepatitis B",

abstract = "A HBV infection is a dynamic disease and long-term liver inflammation contributes to the development of liver cirrhosis and hepatocellular carcinoma. Currently available nucleos(t)ide analogues and pegylated interferon are effective in inhibiting HBV replication but rarely achieve HBsAg clearance. The present article introduces a new definition of HBV cure and several emerging therapies for HBV cure, including direct acting antivirals and immune modulatory antivirals.",

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AU - Yoo, Sun Hong

AU - Kwon, Jung Hyun

PY - 2019/11/25

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N2 - A HBV infection is a dynamic disease and long-term liver inflammation contributes to the development of liver cirrhosis and hepatocellular carcinoma. Currently available nucleos(t)ide analogues and pegylated interferon are effective in inhibiting HBV replication but rarely achieve HBsAg clearance. The present article introduces a new definition of HBV cure and several emerging therapies for HBV cure, including direct acting antivirals and immune modulatory antivirals.

AB - A HBV infection is a dynamic disease and long-term liver inflammation contributes to the development of liver cirrhosis and hepatocellular carcinoma. Currently available nucleos(t)ide analogues and pegylated interferon are effective in inhibiting HBV replication but rarely achieve HBsAg clearance. The present article introduces a new definition of HBV cure and several emerging therapies for HBV cure, including direct acting antivirals and immune modulatory antivirals.

KW - Hepatitis B virus

KW - Therapeutics

UR - https://www.scopus.com/pages/publications/85075494268

U2 - 10.4166/kjg.2019.74.5.267

DO - 10.4166/kjg.2019.74.5.267

M3 - Review article

C2 - 31765555

AN - SCOPUS:85075494268

SN - 1598-9992

VL - 74

SP - 267

EP - 273

JO - The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi

JF - The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi

IS - 5

ER -

New Potential Therapies for Chronic Hepatitis B

Abstract

Keywords

UN SDGs

Access to Document

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