Skip to main navigation Skip to search Skip to main content

One-step transesterification reaction using methanol-stable lipase for omega-3 fatty acid ethyl ester production

  • Griselda Herman Natadiputri
  • , Antonius Suwanto
  • , Hyung Kwoun Kim
  • Atma Jaya Catholic University of Indonesia

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

We investigated transesterification activity of methanol-stable lipase from Staphylococcus haemolyticus L62. Lipase L62 transesterified olive oil and menhaden oil using various alcohols including methanol, ethanol, 1-propanol, and 1-butanol. Based on the high stability of lipase L62 toward alcohols, high molar ratios (3:1 or 6:1) of alcohol to oil were employed in the reaction systems. Lipase L62 produced fatty acid esters efficiently by one-step transesterification. Reaction conditions for production of fatty acid methyl esters (FAMEs) and omega-3 fatty acid ethyl esters were further optimized. Lipase L62 produced those esters efficiently when 30–40 % water content was present in the reaction medium. The lipase L62 conversion yield was as high as 92 % for FAME and omega-3 ethyl ester production. These results indicate that lipase L62 is a suitable catalyst for producing an omega-3 ethyl ester concentrate in the pharmaceutical industry as well as for producing biodiesel in the bio-refinery industry.

Original languageEnglish
Pages (from-to)195-202
Number of pages8
JournalJournal of the Korean Society for Applied Biological Chemistry
Volume58
Issue number2
DOIs
StatePublished - Apr 2015

Bibliographical note

Publisher Copyright:
© 2015, The Korean Society for Applied Biological Chemistry.

Keywords

  • Biodiesel
  • Lipase
  • Omega-3 ethyl ester
  • Staphylococcus haemolyticus L62
  • Transesterification

Fingerprint

Dive into the research topics of 'One-step transesterification reaction using methanol-stable lipase for omega-3 fatty acid ethyl ester production'. Together they form a unique fingerprint.

Cite this