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PCL particle-loaded PLGA solution as injectable bulking agent

  • Hannam University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The morphology, injectability, volume change and tissue ingrowth of the polycarprolactone (PCL)-loaded poly(DL-lactic-co-glycolic acid) (PLGA) using an animal model was investigated. It was observed that the PCL particles were fabricated by a phase separation method and these particles were then mixed with PLGA solution. The PCL particles fabricated by a phase separation method shows a spherical shape having several sizes. The results suggests that the PCL particle loaded-PLGA system shows good injectabilty, volume retention and tissue ingrowth ability that can be an effective injectable bulking agent for the treatment of urinary incontinence.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Pages1059
Number of pages1
StatePublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 17 May 200421 May 2004

Publication series

NameTransactions - 7th World Biomaterials Congress

Conference

ConferenceTransactions - 7th World Biomaterials Congress
Country/TerritoryAustralia
CitySydney
Period17/05/0421/05/04

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