Photonic hydrogel sensors

Ali K. Yetisen; Haider Butt; Lisa R. Volpatti; Ida Pavlichenko; Matjaž Humar; Sheldon J.J. Kwok; Heebeom Koo; Ki Su Kim; Izabela Naydenova; Ali Khademhosseini; Sei Kwang Hahn; Seok Hyun Yun

doi:10.1016/j.biotechadv.2015.10.005

Photonic hydrogel sensors

Ali K. Yetisen
, Haider Butt
, Lisa R. Volpatti
, Ida Pavlichenko
, Matjaž Humar
, Sheldon J.J. Kwok
, Heebeom Koo
, Ki Su Kim
, Izabela Naydenova
, Ali Khademhosseini
, Sei Kwang Hahn
, Seok Hyun Yun

Department of Biomedicine & Health Science

Massachusetts General Hospital
University of Birmingham
Massachusetts Institute of Technology
Harvard University
Jožef Stefan Institute
Technological University Dublin
Brigham and Women’s Hospital
King Abdulaziz University
Konkuk University
Pohang University of Science and Technology

Research output: Contribution to journal › Review article › peer-review

177 Scopus citations

Abstract

Analyte-sensitive hydrogels that incorporate optical structures have emerged as sensing platforms for point-of-care diagnostics. The optical properties of the hydrogel sensors can be rationally designed and fabricated through self-assembly, microfabrication or laser writing. The advantages of photonic hydrogel sensors over conventional assay formats include label-free, quantitative, reusable, and continuous measurement capability that can be integrated with equipment-free text or image display. This Review explains the operation principles of photonic hydrogel sensors, presents syntheses of stimuli-responsive polymers, and provides an overview of qualitative and quantitative readout technologies. Applications in clinical samples are discussed, and potential future directions are identified.

Original language	English
Pages (from-to)	250-271
Number of pages	22
Journal	Biotechnology Advances
Volume	34
Issue number	3
DOIs	https://doi.org/10.1016/j.biotechadv.2015.10.005
State	Published - 1 May 2016

Bibliographical note

Publisher Copyright:
© 2015 Elsevier Inc.

Keywords

Block copolymers
Bragg stacks
Crystalline colloidal arrays
Holography
Hydrogels
In vitro diagnostics
Inverse opals
Layer-by-layer deposition
Photonic crystals
Plasmonics

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10.1016/j.biotechadv.2015.10.005

Cite this

@article{f299286865964fe4a65486cbcbd46bee,

title = "Photonic hydrogel sensors",

abstract = "Analyte-sensitive hydrogels that incorporate optical structures have emerged as sensing platforms for point-of-care diagnostics. The optical properties of the hydrogel sensors can be rationally designed and fabricated through self-assembly, microfabrication or laser writing. The advantages of photonic hydrogel sensors over conventional assay formats include label-free, quantitative, reusable, and continuous measurement capability that can be integrated with equipment-free text or image display. This Review explains the operation principles of photonic hydrogel sensors, presents syntheses of stimuli-responsive polymers, and provides an overview of qualitative and quantitative readout technologies. Applications in clinical samples are discussed, and potential future directions are identified.",

keywords = "Block copolymers, Bragg stacks, Crystalline colloidal arrays, Holography, Hydrogels, In vitro diagnostics, Inverse opals, Layer-by-layer deposition, Photonic crystals, Plasmonics",

author = "Yetisen, \{Ali K.\} and Haider Butt and Volpatti, \{Lisa R.\} and Ida Pavlichenko and Matja{\v z} Humar and Kwok, \{Sheldon J.J.\} and Heebeom Koo and Kim, \{Ki Su\} and Izabela Naydenova and Ali Khademhosseini and Hahn, \{Sei Kwang\} and Yun, \{Seok Hyun\}",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",

year = "2016",

month = may,

day = "1",

doi = "10.1016/j.biotechadv.2015.10.005",

language = "English",

volume = "34",

pages = "250--271",

journal = "Biotechnology Advances",

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T1 - Photonic hydrogel sensors

AU - Yetisen, Ali K.

AU - Butt, Haider

AU - Volpatti, Lisa R.

AU - Pavlichenko, Ida

AU - Humar, Matjaž

AU - Kwok, Sheldon J.J.

AU - Koo, Heebeom

AU - Kim, Ki Su

AU - Naydenova, Izabela

AU - Khademhosseini, Ali

AU - Hahn, Sei Kwang

AU - Yun, Seok Hyun

PY - 2016/5/1

Y1 - 2016/5/1

N2 - Analyte-sensitive hydrogels that incorporate optical structures have emerged as sensing platforms for point-of-care diagnostics. The optical properties of the hydrogel sensors can be rationally designed and fabricated through self-assembly, microfabrication or laser writing. The advantages of photonic hydrogel sensors over conventional assay formats include label-free, quantitative, reusable, and continuous measurement capability that can be integrated with equipment-free text or image display. This Review explains the operation principles of photonic hydrogel sensors, presents syntheses of stimuli-responsive polymers, and provides an overview of qualitative and quantitative readout technologies. Applications in clinical samples are discussed, and potential future directions are identified.

AB - Analyte-sensitive hydrogels that incorporate optical structures have emerged as sensing platforms for point-of-care diagnostics. The optical properties of the hydrogel sensors can be rationally designed and fabricated through self-assembly, microfabrication or laser writing. The advantages of photonic hydrogel sensors over conventional assay formats include label-free, quantitative, reusable, and continuous measurement capability that can be integrated with equipment-free text or image display. This Review explains the operation principles of photonic hydrogel sensors, presents syntheses of stimuli-responsive polymers, and provides an overview of qualitative and quantitative readout technologies. Applications in clinical samples are discussed, and potential future directions are identified.

KW - Block copolymers

KW - Bragg stacks

KW - Crystalline colloidal arrays

KW - Holography

KW - Hydrogels

KW - In vitro diagnostics

KW - Inverse opals

KW - Layer-by-layer deposition

KW - Photonic crystals

KW - Plasmonics

UR - https://www.scopus.com/pages/publications/84951743073

U2 - 10.1016/j.biotechadv.2015.10.005

DO - 10.1016/j.biotechadv.2015.10.005

M3 - Review article

C2 - 26485407

AN - SCOPUS:84951743073

SN - 0734-9750

VL - 34

SP - 250

EP - 271

JO - Biotechnology Advances

JF - Biotechnology Advances

IS - 3

ER -

Photonic hydrogel sensors

Abstract

Bibliographical note

Keywords

Access to Document

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