Platelet count alterations associated with escitalopram, venlafaxine and bupropion in depressive patients

Hoo Rim Song; Young Eun Jung; Hee Ryung Wang; Young Sup Woo; Tae Youn Jun; Won Myong Bahk

doi:10.1111/j.1440-1819.2012.02355.x

Platelet count alterations associated with escitalopram, venlafaxine and bupropion in depressive patients

Hoo Rim Song
, Young Eun Jung
, Hee Ryung Wang
, Young Sup Woo
, Tae Youn Jun
, Won Myong Bahk

Department of Psychiatry

Catholic University of Korea

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

The objective of the present study was to evaluate changes in platelet counts on three different kinds of antidepressant. All subjects (n = 131) in their drug-naïve state had been diagnosed with depression. Escitalopram (n = 42), venlafaxine (n = 50) and bupropion (n = 39) were prescribed, and platelet count was measured before and after 1 month of treatment and compared. Decrease in platelet count on escitalopram was significant, while the others were not. These findings suggest that escitalopram may be associated with decreased platelet count, and bupropion is less likely to exert an influence on platelet count.

Original language	English
Pages (from-to)	457-459
Number of pages	3
Journal	Psychiatry and Clinical Neurosciences
Volume	66
Issue number	5
DOIs	https://doi.org/10.1111/j.1440-1819.2012.02355.x
State	Published - Aug 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

bupropion
escitalopram
platelet count
venlafaxine

Access to Document

10.1111/j.1440-1819.2012.02355.x

Cite this

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title = "Platelet count alterations associated with escitalopram, venlafaxine and bupropion in depressive patients",

abstract = "The objective of the present study was to evaluate changes in platelet counts on three different kinds of antidepressant. All subjects (n = 131) in their drug-na{\"i}ve state had been diagnosed with depression. Escitalopram (n = 42), venlafaxine (n = 50) and bupropion (n = 39) were prescribed, and platelet count was measured before and after 1 month of treatment and compared. Decrease in platelet count on escitalopram was significant, while the others were not. These findings suggest that escitalopram may be associated with decreased platelet count, and bupropion is less likely to exert an influence on platelet count.",

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author = "Song, \{Hoo Rim\} and Jung, \{Young Eun\} and Wang, \{Hee Ryung\} and Woo, \{Young Sup\} and Jun, \{Tae Youn\} and Bahk, \{Won Myong\}",

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doi = "10.1111/j.1440-1819.2012.02355.x",

language = "English",

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T1 - Platelet count alterations associated with escitalopram, venlafaxine and bupropion in depressive patients

AU - Song, Hoo Rim

AU - Jung, Young Eun

AU - Wang, Hee Ryung

AU - Woo, Young Sup

AU - Jun, Tae Youn

AU - Bahk, Won Myong

PY - 2012/8

Y1 - 2012/8

N2 - The objective of the present study was to evaluate changes in platelet counts on three different kinds of antidepressant. All subjects (n = 131) in their drug-naïve state had been diagnosed with depression. Escitalopram (n = 42), venlafaxine (n = 50) and bupropion (n = 39) were prescribed, and platelet count was measured before and after 1 month of treatment and compared. Decrease in platelet count on escitalopram was significant, while the others were not. These findings suggest that escitalopram may be associated with decreased platelet count, and bupropion is less likely to exert an influence on platelet count.

AB - The objective of the present study was to evaluate changes in platelet counts on three different kinds of antidepressant. All subjects (n = 131) in their drug-naïve state had been diagnosed with depression. Escitalopram (n = 42), venlafaxine (n = 50) and bupropion (n = 39) were prescribed, and platelet count was measured before and after 1 month of treatment and compared. Decrease in platelet count on escitalopram was significant, while the others were not. These findings suggest that escitalopram may be associated with decreased platelet count, and bupropion is less likely to exert an influence on platelet count.

KW - bupropion

KW - escitalopram

KW - platelet count

KW - venlafaxine

UR - https://www.scopus.com/pages/publications/84864411927

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DO - 10.1111/j.1440-1819.2012.02355.x

M3 - Article

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AN - SCOPUS:84864411927

SN - 1323-1316

VL - 66

SP - 457

EP - 459

JO - Psychiatry and Clinical Neurosciences

JF - Psychiatry and Clinical Neurosciences

IS - 5

ER -

Platelet count alterations associated with escitalopram, venlafaxine and bupropion in depressive patients

Abstract

UN SDGs

Keywords

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