Abstract
Bare metal stents (BMSs) have been studied in the treatment of tubular organ occlusion, but restenosis remains a problem with this type of therapy. Drug eluting stents (DESs) were developed afterwards to treat and prevent re-stenosis. Clinical studied have proven the efficacy of DESs for the prevention of smooth muscle and cancer cell proliferations. Coating DESs with a polymer facilitates sustained drug release by diffusion, degradation, and osmosis. To control drug delivery in DESs, the drug and polymeric materials-including their physicochemical properties-must be taken into consideration. It is important to understand polymeric materials for the development drug delivery technologies. This review highlights the studies on drug delivery system based on polymeric material used in DESs and the role of polymeric materials in DESs for drug delivery.
| Original language | English |
|---|---|
| Pages (from-to) | 317-324 |
| Number of pages | 8 |
| Journal | Journal of Pharmaceutical Investigation |
| Volume | 46 |
| Issue number | 4 |
| DOIs | |
| State | Published - 1 Jul 2016 |
Bibliographical note
Publisher Copyright:© 2016, The Korean Society of Pharmaceutical Sciences and Technology.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
-
SDG 3 Good Health and Well-being
Keywords
- Drug eluting stent
- Drug release control
- Polymer coating
- Polymeric materials
Fingerprint
Dive into the research topics of 'Polymeric materials for drug release system in drug eluting stents'. Together they form a unique fingerprint.Cite this
- APA
- Author
- BIBTEX
- Harvard
- Standard
- RIS
- Vancouver