Prevalence and contributing factors of nonsusceptibility to imipenem or meropenem in extended-spectrum β-lactamase-producing Klebsiella pneumoniae and Escherichia coli

Yeon Joon Park; Jin Kyung Yu; Kang Gyun Park; Yong Gyu Park; Seongok Lee; Soo Young Kim; Seok Hoon Jeong

doi:10.1016/j.diagmicrobio.2010.12.012

Prevalence and contributing factors of nonsusceptibility to imipenem or meropenem in extended-spectrum β-lactamase-producing Klebsiella pneumoniae and Escherichia coli

Yeon Joon Park
, Jin Kyung Yu
, Kang Gyun Park
, Yong Gyu Park
, Seongok Lee
, Soo Young Kim
, Seok Hoon Jeong

Department of Laboratory Medicine

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

Among the extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae and Escherichia coli, 3.9% of K. pneumoniae showed nonsusceptibility to imipenem or meropenem; and their mechanism was the combination of ESBL and/or plasmid-mediated AmpC β-lactamase production and porin loss. The presence of bla _CTX-M-14 and loss of OmpK36 were associated with higher carbapenem MICs.

Original language	English
Pages (from-to)	87-89
Number of pages	3
Journal	Diagnostic Microbiology and Infectious Disease
Volume	71
Issue number	1
DOIs	https://doi.org/10.1016/j.diagmicrobio.2010.12.012
State	Published - Sep 2011

Bibliographical note

Funding Information:
We wish to thank all the contributing laboratories that provided isolates for this study. This work was supported by a research grant from the Korea Center for Disease Control (2009-E00520-00).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

BlaCTX-M-14
Carbapenem
OmpK36

Access to Document

10.1016/j.diagmicrobio.2010.12.012

Cite this

Park, Y. J., Yu, J. K., Park, K. G., Park, Y. G., Lee, S., Kim, S. Y., & Jeong, S. H. (2011). Prevalence and contributing factors of nonsusceptibility to imipenem or meropenem in extended-spectrum β-lactamase-producing Klebsiella pneumoniae and Escherichia coli. Diagnostic Microbiology and Infectious Disease, 71(1), 87-89. https://doi.org/10.1016/j.diagmicrobio.2010.12.012

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title = "Prevalence and contributing factors of nonsusceptibility to imipenem or meropenem in extended-spectrum β-lactamase-producing Klebsiella pneumoniae and Escherichia coli",

abstract = "Among the extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae and Escherichia coli, 3.9\% of K. pneumoniae showed nonsusceptibility to imipenem or meropenem; and their mechanism was the combination of ESBL and/or plasmid-mediated AmpC β-lactamase production and porin loss. The presence of bla CTX-M-14 and loss of OmpK36 were associated with higher carbapenem MICs.",

keywords = "BlaCTX-M-14, Carbapenem, OmpK36",

author = "Park, \{Yeon Joon\} and Yu, \{Jin Kyung\} and Park, \{Kang Gyun\} and Park, \{Yong Gyu\} and Seongok Lee and Kim, \{Soo Young\} and Jeong, \{Seok Hoon\}",

note = "Funding Information: We wish to thank all the contributing laboratories that provided isolates for this study. This work was supported by a research grant from the Korea Center for Disease Control (2009-E00520-00).",

year = "2011",

month = sep,

doi = "10.1016/j.diagmicrobio.2010.12.012",

language = "English",

volume = "71",

pages = "87--89",

journal = "Diagnostic Microbiology and Infectious Disease",

issn = "0732-8893",

publisher = "Elsevier Inc.",

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}

Prevalence and contributing factors of nonsusceptibility to imipenem or meropenem in extended-spectrum β-lactamase-producing Klebsiella pneumoniae and Escherichia coli. / Park, Yeon Joon; Yu, Jin Kyung; Park, Kang Gyun et al.
In: Diagnostic Microbiology and Infectious Disease, Vol. 71, No. 1, 09.2011, p. 87-89.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Prevalence and contributing factors of nonsusceptibility to imipenem or meropenem in extended-spectrum β-lactamase-producing Klebsiella pneumoniae and Escherichia coli

AU - Park, Yeon Joon

AU - Yu, Jin Kyung

AU - Park, Kang Gyun

AU - Park, Yong Gyu

AU - Lee, Seongok

AU - Kim, Soo Young

AU - Jeong, Seok Hoon

N1 - Funding Information: We wish to thank all the contributing laboratories that provided isolates for this study. This work was supported by a research grant from the Korea Center for Disease Control (2009-E00520-00).

PY - 2011/9

Y1 - 2011/9

N2 - Among the extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae and Escherichia coli, 3.9% of K. pneumoniae showed nonsusceptibility to imipenem or meropenem; and their mechanism was the combination of ESBL and/or plasmid-mediated AmpC β-lactamase production and porin loss. The presence of bla CTX-M-14 and loss of OmpK36 were associated with higher carbapenem MICs.

AB - Among the extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae and Escherichia coli, 3.9% of K. pneumoniae showed nonsusceptibility to imipenem or meropenem; and their mechanism was the combination of ESBL and/or plasmid-mediated AmpC β-lactamase production and porin loss. The presence of bla CTX-M-14 and loss of OmpK36 were associated with higher carbapenem MICs.

KW - BlaCTX-M-14

KW - Carbapenem

KW - OmpK36

UR - https://www.scopus.com/pages/publications/80051667066

U2 - 10.1016/j.diagmicrobio.2010.12.012

DO - 10.1016/j.diagmicrobio.2010.12.012

M3 - Article

C2 - 21397426

AN - SCOPUS:80051667066

SN - 0732-8893

VL - 71

SP - 87

EP - 89

JO - Diagnostic Microbiology and Infectious Disease

JF - Diagnostic Microbiology and Infectious Disease

IS - 1

ER -

Prevalence and contributing factors of nonsusceptibility to imipenem or meropenem in extended-spectrum β-lactamase-producing Klebsiella pneumoniae and Escherichia coli

Abstract

Bibliographical note

UN SDGs

Keywords

Access to Document

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