Quinone oxidoreductase (NQO1) gene polymorphism may not confer a susceptibility to mood disorders

Chi Un Pae; Soo Jung Yoon; Ashwin A. Patkar; Jung Jin Kim; Chul Lee; In Ho Paik

doi:10.1016/j.psychres.2006.01.011

Quinone oxidoreductase (NQO1) gene polymorphism may not confer a susceptibility to mood disorders

Chi Un Pae
, Soo Jung Yoon
, Ashwin A. Patkar
, Jung Jin Kim
, Chul Lee
, In Ho Paik

Department of Psychiatry

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Quinone oxidoreductase (NQO1) plays a key role in the cellular antioxidant defense by detoxifying quinine derivatives. Case-control association study of the possible relationship between the NQO1 gene polymorphism and mood disorders (patients with major depressive disorder, n = 61; patients with bipolar I disorder, n = 80; control, n = 106) was carried out using PCR-based techniques. These preliminary results showed that the NQO1 gene polymorphism was not related to a susceptibility to mood disorders.

Original language	English
Pages (from-to)	83-86
Number of pages	4
Journal	Psychiatry Research
Volume	153
Issue number	1
DOIs	https://doi.org/10.1016/j.psychres.2006.01.011
State	Published - 30 Sep 2007

Bibliographical note

Funding Information:
This study was supported by a grant (KRF-2004-003-E00145) from the Korea Research Foundation. The authors express their sincere gratitude to all the patients who participated in the study.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Mood disorder
NQO1 gene
Polymorphism

Access to Document

10.1016/j.psychres.2006.01.011

Cite this

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title = "Quinone oxidoreductase (NQO1) gene polymorphism may not confer a susceptibility to mood disorders",

abstract = "Quinone oxidoreductase (NQO1) plays a key role in the cellular antioxidant defense by detoxifying quinine derivatives. Case-control association study of the possible relationship between the NQO1 gene polymorphism and mood disorders (patients with major depressive disorder, n = 61; patients with bipolar I disorder, n = 80; control, n = 106) was carried out using PCR-based techniques. These preliminary results showed that the NQO1 gene polymorphism was not related to a susceptibility to mood disorders.",

keywords = "Mood disorder, NQO1 gene, Polymorphism",

author = "Pae, \{Chi Un\} and Yoon, \{Soo Jung\} and Patkar, \{Ashwin A.\} and Kim, \{Jung Jin\} and Chul Lee and Paik, \{In Ho\}",

note = "Funding Information: This study was supported by a grant (KRF-2004-003-E00145) from the Korea Research Foundation. The authors express their sincere gratitude to all the patients who participated in the study. ",

year = "2007",

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doi = "10.1016/j.psychres.2006.01.011",

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T1 - Quinone oxidoreductase (NQO1) gene polymorphism may not confer a susceptibility to mood disorders

AU - Pae, Chi Un

AU - Yoon, Soo Jung

AU - Patkar, Ashwin A.

AU - Kim, Jung Jin

AU - Lee, Chul

AU - Paik, In Ho

N1 - Funding Information: This study was supported by a grant (KRF-2004-003-E00145) from the Korea Research Foundation. The authors express their sincere gratitude to all the patients who participated in the study.

PY - 2007/9/30

Y1 - 2007/9/30

N2 - Quinone oxidoreductase (NQO1) plays a key role in the cellular antioxidant defense by detoxifying quinine derivatives. Case-control association study of the possible relationship between the NQO1 gene polymorphism and mood disorders (patients with major depressive disorder, n = 61; patients with bipolar I disorder, n = 80; control, n = 106) was carried out using PCR-based techniques. These preliminary results showed that the NQO1 gene polymorphism was not related to a susceptibility to mood disorders.

AB - Quinone oxidoreductase (NQO1) plays a key role in the cellular antioxidant defense by detoxifying quinine derivatives. Case-control association study of the possible relationship between the NQO1 gene polymorphism and mood disorders (patients with major depressive disorder, n = 61; patients with bipolar I disorder, n = 80; control, n = 106) was carried out using PCR-based techniques. These preliminary results showed that the NQO1 gene polymorphism was not related to a susceptibility to mood disorders.

KW - Mood disorder

KW - NQO1 gene

KW - Polymorphism

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DO - 10.1016/j.psychres.2006.01.011

M3 - Article

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AN - SCOPUS:34548500771

SN - 0165-1781

VL - 153

SP - 83

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JO - Psychiatry Research

JF - Psychiatry Research

IS - 1

ER -

Quinone oxidoreductase (NQO1) gene polymorphism may not confer a susceptibility to mood disorders

Abstract

Bibliographical note

UN SDGs

Keywords

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