TY - JOUR
T1 - Radiofrequency induced lesion characteristics according to force-time integral in experimental model
AU - Hwang, You Mi
AU - Lee, Woo Seok
AU - Choi, Kee Joon
AU - Kim, Yoo Ri
N1 - Publisher Copyright:
© 2021 Lippincott Williams and Wilkins. All rights reserved.
PY - 2021/3/12
Y1 - 2021/3/12
N2 - Contact force (CF)-sensing technology has enabled accurate real-time CF measurement in tissue. Average CF, which is quantified by the force-time integral (FTI), correlates with lesion volume.Little is known about which of the time and force factors that compose FTI plays a more important role and which is a better index for predicting lesion size, FTI, or force-power-time index (FPTI). Investigators sought to identify a better index for predicting radiofrequency ablation lesion formation with experimental model.Radiofrequency current was delivered to the swine skeletal muscle at radiofrequency energy current was delivered at 4 fixed power settings (15, 25, 30, and 40 W) for 6 variable time durations (5, 10, 20, 30, 40, and 50 s) with 6 variable CF settings (5, 10, 20, 30, 40, and 50 g). At each setting, the following parameters were evaluated:(1)transmural lesion depth,(2)lesion width, and(3)lesion volume.Between FTI factors, the time factor was more important than the force factor for lesion formation. The area under the curve was greater for FPTI (0.943) than for FTI (0.870). On univariate linear regression analysis, the explanatory power of the linear regression model was better explained by FPTI (56.4%) than FTI (32.1%).Under the same FTI condition, the time factor had a greater effect on lesion formation. When power was included, the power factor had a greater effect on lesion formation and steam pop.
AB - Contact force (CF)-sensing technology has enabled accurate real-time CF measurement in tissue. Average CF, which is quantified by the force-time integral (FTI), correlates with lesion volume.Little is known about which of the time and force factors that compose FTI plays a more important role and which is a better index for predicting lesion size, FTI, or force-power-time index (FPTI). Investigators sought to identify a better index for predicting radiofrequency ablation lesion formation with experimental model.Radiofrequency current was delivered to the swine skeletal muscle at radiofrequency energy current was delivered at 4 fixed power settings (15, 25, 30, and 40 W) for 6 variable time durations (5, 10, 20, 30, 40, and 50 s) with 6 variable CF settings (5, 10, 20, 30, 40, and 50 g). At each setting, the following parameters were evaluated:(1)transmural lesion depth,(2)lesion width, and(3)lesion volume.Between FTI factors, the time factor was more important than the force factor for lesion formation. The area under the curve was greater for FPTI (0.943) than for FTI (0.870). On univariate linear regression analysis, the explanatory power of the linear regression model was better explained by FPTI (56.4%) than FTI (32.1%).Under the same FTI condition, the time factor had a greater effect on lesion formation. When power was included, the power factor had a greater effect on lesion formation and steam pop.
KW - cardiac electrophysiology
KW - catheter ablation
KW - radiofrequency ablation
UR - http://www.scopus.com/inward/record.url?scp=85103072601&partnerID=8YFLogxK
U2 - 10.1097/MD.0000000000025126
DO - 10.1097/MD.0000000000025126
M3 - Article
C2 - 33725912
AN - SCOPUS:85103072601
SN - 0025-7974
VL - 100
SP - E25126
JO - Medicine (United States)
JF - Medicine (United States)
IS - 10
ER -