Rodent animal research in utx

Randa Akouri; Min Jong Song; Cesar Diaz Garcia

doi:10.1007/978-3-319-94162-2_5

Rodent animal research in utx

Randa Akouri
, Min Jong Song
, Cesar Diaz Garcia

Department of Obstetrics and Gynecology

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

The rodents, mouse, and rat represent well-characterized animal sources for basic research in any field of biological sciences. The animals are cheap compared to other type of animals, easy to husbandry, and are extremely well characterized from genetic and physiology point of views, especially when it comes to immunological and reproductive aspects. Availability of gene-modified strains, easy embryo transfer, and the accessibility of specific recombinant proteins and monoclonal antibodies are further advantages. Hence, the first experiments done in the modern era of uterus transplantation used mouse and rat as the main animal models. In this chapter, we describe important key steps of the uterus transplantation procedure with research in rodents, including surgical technique, ischemia-reperfusion damage, rejection patterns, immunosuppression, and fertility.

Original language	English
Title of host publication	Uterus Transplantation
Publisher	Springer International Publishing
Pages	39-50
Number of pages	12
ISBN (Electronic)	9783319941622
ISBN (Print)	9783319941615
DOIs	https://doi.org/10.1007/978-3-319-94162-2_5
State	Published - 1 Jan 2019

Bibliographical note

Publisher Copyright:
© Springer Nature Switzerland AG 2020.

Access to Document

10.1007/978-3-319-94162-2_5

Cite this

@inbook{26c466cf8b9748ea838b3305099820e8,

title = "Rodent animal research in utx",

abstract = "The rodents, mouse, and rat represent well-characterized animal sources for basic research in any field of biological sciences. The animals are cheap compared to other type of animals, easy to husbandry, and are extremely well characterized from genetic and physiology point of views, especially when it comes to immunological and reproductive aspects. Availability of gene-modified strains, easy embryo transfer, and the accessibility of specific recombinant proteins and monoclonal antibodies are further advantages. Hence, the first experiments done in the modern era of uterus transplantation used mouse and rat as the main animal models. In this chapter, we describe important key steps of the uterus transplantation procedure with research in rodents, including surgical technique, ischemia-reperfusion damage, rejection patterns, immunosuppression, and fertility.",

author = "Randa Akouri and Song, \{Min Jong\} and Garcia, \{Cesar Diaz\}",

note = "Publisher Copyright: {\textcopyright} Springer Nature Switzerland AG 2020.",

year = "2019",

month = jan,

day = "1",

doi = "10.1007/978-3-319-94162-2\_5",

language = "English",

isbn = "9783319941615",

pages = "39--50",

booktitle = "Uterus Transplantation",

publisher = "Springer International Publishing",

}

TY - CHAP

T1 - Rodent animal research in utx

AU - Akouri, Randa

AU - Song, Min Jong

AU - Garcia, Cesar Diaz

PY - 2019/1/1

Y1 - 2019/1/1

N2 - The rodents, mouse, and rat represent well-characterized animal sources for basic research in any field of biological sciences. The animals are cheap compared to other type of animals, easy to husbandry, and are extremely well characterized from genetic and physiology point of views, especially when it comes to immunological and reproductive aspects. Availability of gene-modified strains, easy embryo transfer, and the accessibility of specific recombinant proteins and monoclonal antibodies are further advantages. Hence, the first experiments done in the modern era of uterus transplantation used mouse and rat as the main animal models. In this chapter, we describe important key steps of the uterus transplantation procedure with research in rodents, including surgical technique, ischemia-reperfusion damage, rejection patterns, immunosuppression, and fertility.

AB - The rodents, mouse, and rat represent well-characterized animal sources for basic research in any field of biological sciences. The animals are cheap compared to other type of animals, easy to husbandry, and are extremely well characterized from genetic and physiology point of views, especially when it comes to immunological and reproductive aspects. Availability of gene-modified strains, easy embryo transfer, and the accessibility of specific recombinant proteins and monoclonal antibodies are further advantages. Hence, the first experiments done in the modern era of uterus transplantation used mouse and rat as the main animal models. In this chapter, we describe important key steps of the uterus transplantation procedure with research in rodents, including surgical technique, ischemia-reperfusion damage, rejection patterns, immunosuppression, and fertility.

UR - https://www.scopus.com/pages/publications/85085457533

U2 - 10.1007/978-3-319-94162-2_5

DO - 10.1007/978-3-319-94162-2_5

M3 - Chapter

AN - SCOPUS:85085457533

SN - 9783319941615

SP - 39

EP - 50

BT - Uterus Transplantation

PB - Springer International Publishing

ER -

Rodent animal research in utx

Abstract

Bibliographical note

Access to Document

Other files and links

Fingerprint

Cite this