Target-specific rCBF changes induced by 0.3-T static magnetic field exposure on the brain

Seungyeon Kim; Yong An Chung; Chang Uk Lee; Jeong Ho Chae; Rahyeong Juh; Jaeseung Jeong

doi:10.1016/j.brainres.2009.10.057

Target-specific rCBF changes induced by 0.3-T static magnetic field exposure on the brain

Seungyeon Kim
, Yong An Chung
, Chang Uk Lee
, Jeong Ho Chae
, Rahyeong Juh
, Jaeseung Jeong

Department of Psychiatry

Korea Advanced Institute of Science and Technology
The Catholic University of Korea

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

The magnetic field has been regarded as both harmful and beneficial for its applications on human brains including transcranial magnetic stimulation (TMS), but its effects still remain in question. Here, we determined using single photon emission computed tomography (SPECT) if 0.3-T static magnetic field could alter regional cerebral blood flow (rCBF) in target and other brain regions in healthy subjects. The permanent static magnet (0.3 T, unipolar, disk shaped, 4 cm diameter and 1 cm thick) was placed on the right frontotemporal region of the brain for each of 14 healthy subjects. Tc-99m ECD perfusion SPECT was taken to compare the CBF patterns in the subjects exposed to the static magnet field with those of the resting and sham conditions. We found that the rCBF was significantly increased in the right frontal and parietal regions and the right insula. On the other hand, rCBF was rather decreased in the left frontal and left parietal regions (P < 0.05). These results of this basic study suggest that 0.3-T static magnetic field induces an increase in rCBF in the targeted brain areas non-invasively, which may result from a decrease in rCBF in contralateral regions.

Original language	English
Pages (from-to)	211-217
Number of pages	7
Journal	Brain Research
Volume	1317
DOIs	https://doi.org/10.1016/j.brainres.2009.10.057
State	Published - 4 Mar 2010

Bibliographical note

Funding Information:
The authors wish to acknowledge the financial support of the Catholic Medical Center Research Foundation made in the program year of 2008. This work was also supported by grants from the Korea Science and Engineering Foundation (KOSEF) grant funded by the Korean government (MOST) (No. M10644000005-06N4400-00510 , No. R01-2007-000-21094-0 and No. M10644000013-06N4400-01310 ).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cerebral blood flow
SPECT
SPM
Static magnetic field

Access to Document

10.1016/j.brainres.2009.10.057

Cite this

@article{b40ecc1d020343a98807370a94cab9df,

title = "Target-specific rCBF changes induced by 0.3-T static magnetic field exposure on the brain",

abstract = "The magnetic field has been regarded as both harmful and beneficial for its applications on human brains including transcranial magnetic stimulation (TMS), but its effects still remain in question. Here, we determined using single photon emission computed tomography (SPECT) if 0.3-T static magnetic field could alter regional cerebral blood flow (rCBF) in target and other brain regions in healthy subjects. The permanent static magnet (0.3 T, unipolar, disk shaped, 4 cm diameter and 1 cm thick) was placed on the right frontotemporal region of the brain for each of 14 healthy subjects. Tc-99m ECD perfusion SPECT was taken to compare the CBF patterns in the subjects exposed to the static magnet field with those of the resting and sham conditions. We found that the rCBF was significantly increased in the right frontal and parietal regions and the right insula. On the other hand, rCBF was rather decreased in the left frontal and left parietal regions (P < 0.05). These results of this basic study suggest that 0.3-T static magnetic field induces an increase in rCBF in the targeted brain areas non-invasively, which may result from a decrease in rCBF in contralateral regions.",

keywords = "Cerebral blood flow, SPECT, SPM, Static magnetic field",

author = "Seungyeon Kim and Chung, \{Yong An\} and Lee, \{Chang Uk\} and Chae, \{Jeong Ho\} and Rahyeong Juh and Jaeseung Jeong",

note = "Funding Information: The authors wish to acknowledge the financial support of the Catholic Medical Center Research Foundation made in the program year of 2008. This work was also supported by grants from the Korea Science and Engineering Foundation (KOSEF) grant funded by the Korean government (MOST) (No. M10644000005-06N4400-00510 , No. R01-2007-000-21094-0 and No. M10644000013-06N4400-01310 ).",

year = "2010",

month = mar,

day = "4",

doi = "10.1016/j.brainres.2009.10.057",

language = "English",

volume = "1317",

pages = "211--217",

journal = "Brain Research",

issn = "0006-8993",

publisher = "Elsevier BV",

}

TY - JOUR

T1 - Target-specific rCBF changes induced by 0.3-T static magnetic field exposure on the brain

AU - Kim, Seungyeon

AU - Chung, Yong An

AU - Lee, Chang Uk

AU - Chae, Jeong Ho

AU - Juh, Rahyeong

AU - Jeong, Jaeseung

N1 - Funding Information: The authors wish to acknowledge the financial support of the Catholic Medical Center Research Foundation made in the program year of 2008. This work was also supported by grants from the Korea Science and Engineering Foundation (KOSEF) grant funded by the Korean government (MOST) (No. M10644000005-06N4400-00510 , No. R01-2007-000-21094-0 and No. M10644000013-06N4400-01310 ).

PY - 2010/3/4

Y1 - 2010/3/4

N2 - The magnetic field has been regarded as both harmful and beneficial for its applications on human brains including transcranial magnetic stimulation (TMS), but its effects still remain in question. Here, we determined using single photon emission computed tomography (SPECT) if 0.3-T static magnetic field could alter regional cerebral blood flow (rCBF) in target and other brain regions in healthy subjects. The permanent static magnet (0.3 T, unipolar, disk shaped, 4 cm diameter and 1 cm thick) was placed on the right frontotemporal region of the brain for each of 14 healthy subjects. Tc-99m ECD perfusion SPECT was taken to compare the CBF patterns in the subjects exposed to the static magnet field with those of the resting and sham conditions. We found that the rCBF was significantly increased in the right frontal and parietal regions and the right insula. On the other hand, rCBF was rather decreased in the left frontal and left parietal regions (P < 0.05). These results of this basic study suggest that 0.3-T static magnetic field induces an increase in rCBF in the targeted brain areas non-invasively, which may result from a decrease in rCBF in contralateral regions.

AB - The magnetic field has been regarded as both harmful and beneficial for its applications on human brains including transcranial magnetic stimulation (TMS), but its effects still remain in question. Here, we determined using single photon emission computed tomography (SPECT) if 0.3-T static magnetic field could alter regional cerebral blood flow (rCBF) in target and other brain regions in healthy subjects. The permanent static magnet (0.3 T, unipolar, disk shaped, 4 cm diameter and 1 cm thick) was placed on the right frontotemporal region of the brain for each of 14 healthy subjects. Tc-99m ECD perfusion SPECT was taken to compare the CBF patterns in the subjects exposed to the static magnet field with those of the resting and sham conditions. We found that the rCBF was significantly increased in the right frontal and parietal regions and the right insula. On the other hand, rCBF was rather decreased in the left frontal and left parietal regions (P < 0.05). These results of this basic study suggest that 0.3-T static magnetic field induces an increase in rCBF in the targeted brain areas non-invasively, which may result from a decrease in rCBF in contralateral regions.

KW - Cerebral blood flow

KW - SPECT

KW - SPM

KW - Static magnetic field

UR - https://www.scopus.com/pages/publications/76049091869

U2 - 10.1016/j.brainres.2009.10.057

DO - 10.1016/j.brainres.2009.10.057

M3 - Article

C2 - 19879862

AN - SCOPUS:76049091869

SN - 0006-8993

VL - 1317

SP - 211

EP - 217

JO - Brain Research

JF - Brain Research

ER -

Target-specific rCBF changes induced by 0.3-T static magnetic field exposure on the brain

Abstract

Bibliographical note

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this