Tenofovir-associated Fanconi syndrome and nephrotic syndrome in a patient with chronic hepatitis B monoinfection

Hyeon Seok Hwang; Cheol Whee Park; Myeong Jun Song

doi:10.1002/hep.27730

Tenofovir-associated Fanconi syndrome and nephrotic syndrome in a patient with chronic hepatitis B monoinfection

Hyeon Seok Hwang
, Cheol Whee Park
, Myeong Jun Song

Department of Internal Medicine

The Catholic University of Korea

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

Tenofovir disoproxil fumarate (TDF) is widely used as an effective first-line therapy for chronic hepatitis B (CHB) infection. While TDF demonstrates successful viral suppression, it has been linked to the development of renal proximal tubular (PT) dysfunction, leading to Fanconi syndrome. However, Fanconi syndrome has been rarely reported in CHB-monoinfected patients, and there were no reports of TDF-associated nephrotic syndrome. Here, we report a case of combined Fanconi and nephrotic syndrome in CHB patients after TDF exposure.

Original language	English
Pages (from-to)	1318-1320
Number of pages	3
Journal	Hepatology
Volume	62
Issue number	4
DOIs	https://doi.org/10.1002/hep.27730
State	Published - 1 Oct 2015

Bibliographical note

Publisher Copyright:
© 2015 by the American Association for the Study of Liver Diseases.

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10.1002/hep.27730

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title = "Tenofovir-associated Fanconi syndrome and nephrotic syndrome in a patient with chronic hepatitis B monoinfection",

abstract = "Tenofovir disoproxil fumarate (TDF) is widely used as an effective first-line therapy for chronic hepatitis B (CHB) infection. While TDF demonstrates successful viral suppression, it has been linked to the development of renal proximal tubular (PT) dysfunction, leading to Fanconi syndrome. However, Fanconi syndrome has been rarely reported in CHB-monoinfected patients, and there were no reports of TDF-associated nephrotic syndrome. Here, we report a case of combined Fanconi and nephrotic syndrome in CHB patients after TDF exposure.",

author = "Hwang, \{Hyeon Seok\} and Park, \{Cheol Whee\} and Song, \{Myeong Jun\}",

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doi = "10.1002/hep.27730",

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AU - Hwang, Hyeon Seok

AU - Park, Cheol Whee

AU - Song, Myeong Jun

PY - 2015/10/1

Y1 - 2015/10/1

N2 - Tenofovir disoproxil fumarate (TDF) is widely used as an effective first-line therapy for chronic hepatitis B (CHB) infection. While TDF demonstrates successful viral suppression, it has been linked to the development of renal proximal tubular (PT) dysfunction, leading to Fanconi syndrome. However, Fanconi syndrome has been rarely reported in CHB-monoinfected patients, and there were no reports of TDF-associated nephrotic syndrome. Here, we report a case of combined Fanconi and nephrotic syndrome in CHB patients after TDF exposure.

AB - Tenofovir disoproxil fumarate (TDF) is widely used as an effective first-line therapy for chronic hepatitis B (CHB) infection. While TDF demonstrates successful viral suppression, it has been linked to the development of renal proximal tubular (PT) dysfunction, leading to Fanconi syndrome. However, Fanconi syndrome has been rarely reported in CHB-monoinfected patients, and there were no reports of TDF-associated nephrotic syndrome. Here, we report a case of combined Fanconi and nephrotic syndrome in CHB patients after TDF exposure.

UR - https://www.scopus.com/pages/publications/84942551995

U2 - 10.1002/hep.27730

DO - 10.1002/hep.27730

M3 - Article

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JO - Hepatology

JF - Hepatology

IS - 4

ER -

Tenofovir-associated Fanconi syndrome and nephrotic syndrome in a patient with chronic hepatitis B monoinfection

Abstract

Bibliographical note

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