The complete genome sequence and molecular analysis of human hepatitis E virus genotype IV identified from a Korean patient

Haesun Yun; Jin Seon Kim; Hyeok Jin Lee; Sook Hyang Jeong; Jeong Sim Kim; Sang Jong Park; Seong Gyu Hwang; Sook Kyoung Kang; Youngmee Jee; Jong Hyun Kim

doi:10.1007/s00705-010-0661-9

The complete genome sequence and molecular analysis of human hepatitis E virus genotype IV identified from a Korean patient

Haesun Yun
, Jin Seon Kim
, Hyeok Jin Lee
, Sook Hyang Jeong
, Jeong Sim Kim
, Sang Jong Park
, Seong Gyu Hwang
, Sook Kyoung Kang
, Youngmee Jee
, Jong Hyun Kim

Department of Pediatrics

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Hepatitis E virus (HEV) was originally identified as the etiological agent of non-HAV enterically transmitted hepatitis. One HEV strain (FJ763142) was identified from an acute viral hepatitis E patient with IgM anti-HEV in Korea. The complete genome sequence consisted of 7,238 nucleotides (nt) plus a 22-nt poly(A) tail. The strain belongs to genotype IV, with 91% homology compared with AB197674, which was found in a Japanese patient who had traveled to China. This finding suggests that HEV genotype IV already circulates in Korea, and this HEV might be the first example of an indigenous strain.

Original language	English
Pages (from-to)	1003-1008
Number of pages	6
Journal	Archives of Virology
Volume	155
Issue number	6
DOIs	https://doi.org/10.1007/s00705-010-0661-9
State	Published - 2010

Bibliographical note

Funding Information:
This work was supported by Korea National Institute of Health (KNIH; Intramural Fund, Grant No. 4800-4863-300). The authors are grateful to Drs. Mishiro and Takahashi for designing primers to analyze the full genome of Korean HEV.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1007/s00705-010-0661-9

Cite this

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title = "The complete genome sequence and molecular analysis of human hepatitis E virus genotype IV identified from a Korean patient",

abstract = "Hepatitis E virus (HEV) was originally identified as the etiological agent of non-HAV enterically transmitted hepatitis. One HEV strain (FJ763142) was identified from an acute viral hepatitis E patient with IgM anti-HEV in Korea. The complete genome sequence consisted of 7,238 nucleotides (nt) plus a 22-nt poly(A) tail. The strain belongs to genotype IV, with 91\% homology compared with AB197674, which was found in a Japanese patient who had traveled to China. This finding suggests that HEV genotype IV already circulates in Korea, and this HEV might be the first example of an indigenous strain.",

author = "Haesun Yun and Kim, \{Jin Seon\} and Lee, \{Hyeok Jin\} and Jeong, \{Sook Hyang\} and Kim, \{Jeong Sim\} and Park, \{Sang Jong\} and Hwang, \{Seong Gyu\} and Kang, \{Sook Kyoung\} and Youngmee Jee and Kim, \{Jong Hyun\}",

note = "Funding Information: This work was supported by Korea National Institute of Health (KNIH; Intramural Fund, Grant No. 4800-4863-300). The authors are grateful to Drs. Mishiro and Takahashi for designing primers to analyze the full genome of Korean HEV. ",

year = "2010",

doi = "10.1007/s00705-010-0661-9",

language = "English",

volume = "155",

pages = "1003--1008",

journal = "Archives of Virology",

issn = "0304-8608",

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TY - JOUR

T1 - The complete genome sequence and molecular analysis of human hepatitis E virus genotype IV identified from a Korean patient

AU - Yun, Haesun

AU - Kim, Jin Seon

AU - Lee, Hyeok Jin

AU - Jeong, Sook Hyang

AU - Kim, Jeong Sim

AU - Park, Sang Jong

AU - Hwang, Seong Gyu

AU - Kang, Sook Kyoung

AU - Jee, Youngmee

AU - Kim, Jong Hyun

N1 - Funding Information: This work was supported by Korea National Institute of Health (KNIH; Intramural Fund, Grant No. 4800-4863-300). The authors are grateful to Drs. Mishiro and Takahashi for designing primers to analyze the full genome of Korean HEV.

PY - 2010

Y1 - 2010

N2 - Hepatitis E virus (HEV) was originally identified as the etiological agent of non-HAV enterically transmitted hepatitis. One HEV strain (FJ763142) was identified from an acute viral hepatitis E patient with IgM anti-HEV in Korea. The complete genome sequence consisted of 7,238 nucleotides (nt) plus a 22-nt poly(A) tail. The strain belongs to genotype IV, with 91% homology compared with AB197674, which was found in a Japanese patient who had traveled to China. This finding suggests that HEV genotype IV already circulates in Korea, and this HEV might be the first example of an indigenous strain.

AB - Hepatitis E virus (HEV) was originally identified as the etiological agent of non-HAV enterically transmitted hepatitis. One HEV strain (FJ763142) was identified from an acute viral hepatitis E patient with IgM anti-HEV in Korea. The complete genome sequence consisted of 7,238 nucleotides (nt) plus a 22-nt poly(A) tail. The strain belongs to genotype IV, with 91% homology compared with AB197674, which was found in a Japanese patient who had traveled to China. This finding suggests that HEV genotype IV already circulates in Korea, and this HEV might be the first example of an indigenous strain.

UR - https://www.scopus.com/pages/publications/77953322680

U2 - 10.1007/s00705-010-0661-9

DO - 10.1007/s00705-010-0661-9

M3 - Article

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AN - SCOPUS:77953322680

SN - 0304-8608

VL - 155

SP - 1003

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JO - Archives of Virology

JF - Archives of Virology

IS - 6

ER -

The complete genome sequence and molecular analysis of human hepatitis E virus genotype IV identified from a Korean patient

Abstract

Bibliographical note

UN SDGs

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