The gender-dependent association between obesity and age-related cataracts in middle-aged Korean adults

Deok Soon Lee, Kyungdo Han, Hyun Ah Kim, Sae Young Lee, Young Hoon Park, Hyeon Woo Yim, Kang Sook Lee, Won Chul Lee, Yong Gyu Park, Kyung Sun Na, Yong Moon Park

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12 Scopus citations

Abstract

The aim of this study was to investigate the association of central and abdominal obesity with the prevalence of cataracts in a middle-aged Korean population. This retrospective cross-sectional study was based on the data collected from the Korea National Health and Nutrition Examination Survey 2008-2009, in which 4,914 subjects were examined. Ophthalmological examinations were performed to determine the presence of a nuclear, cortical, or posterior subcapsular cataract. Both general obesity (a body mass index ≥25 kg/m2) and abdominal obesity (a waist circumference ≥90 cm for men and ≥80 cm for women) were significantly associated with the occurrence of cataracts among middle-aged women [adjusted odds ratio (aOR), 1.32; 95% confidence interval (CI), 1.03-1.69; and aOR, 1.40; 95% CI, 1.06-1.85, respectively], while abdominal obesity was significantly inversely associated with the occurrence of cataracts among middle-aged men (aOR, 0.76; 95% CI, 0.58-1.01; and aOR, 0.66; 95% CI, 0.49-0.89, respectively). We report a difference in the association between obesity and the prevalence of cataracts based on gender.

Original languageEnglish
Article numbere0124262
JournalPLoS ONE
Volume10
Issue number5
DOIs
StatePublished - 14 May 2015

Bibliographical note

Publisher Copyright:
© 2015 Lee et al.

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