The past, present and future of heart transplantation

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129 Scopus citations

Abstract

Heart transplantation (HTx) has become standard treatment for selected patients with end-stage heart failure. Improvements in immunosuppressant, donor procurement, surgical techniques, and post-HTx care have resulted in a substantial decrease in acute allograft rejection, which had previously significantly limited survival of HTx recipients. However, limitations to long-term allograft survival exist, including rejection, infection, coronary allograft vasculopathy, and malignancy. Careful balance of immunosuppressive therapy and vigilant surveillance for complications can further improve long-term outcomes of HTx recipients.

Original languageEnglish
Pages (from-to)565-589
Number of pages25
JournalKorean Circulation Journal
Volume48
Issue number7
DOIs
StatePublished - Jul 2018

Bibliographical note

Publisher Copyright:
Copyright © 2018. The Korean Society of Cardiology.

Keywords

  • Current practice
  • Forecasting
  • Heart failure
  • Heart transplantation
  • History

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