Therapeutic hypothermia after cardiac arrest during living-donor liver transplant surgery: A case report

Jaesik Park, Ju Eun Kwak, Yun Jeong Cho, Ho Joong Choi, Hoon Choi, Min Suk Chae, Chul Soo Park, Jong Ho Choi, Sang Hyun Hong

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Rationale:Therapeutic hypothermia is an effective medical treatment for neurological recovery after cardiac arrest. Here, we describe a case of successful mild therapeutic hypothermia after cardiac arrest during living-donor liver transplantation.Patient concerns:A 54-year-old woman with alcoholic liver cirrhosis was admitted for living-donor liver transplantation. Cardiac arrest occurred during the anhepatic phase. After cardiopulmonary resuscitation, spontaneous circulation returned, but the bispectral index level remained below 10 until the end of surgery.Diagnoses:Neurological injury caused by global cerebral hypoperfusion was suspected.Interventions:The patient was treated with mild therapeutic hypothermia for 24hours after resuscitation targeting a core body temperature of 34°C with surface cooling using ice bags.Outcomes:The patient recovered consciousness about 22 hours after the event. However, she showed symptoms of delirium even when discharged. At the 3-month follow-up exam, she showed no specific neurological complications. The transplanted liver showed no problems with regeneration.Lessons:Mild therapeutic hypothermia may be safely adopted in cases of cardiac arrest in liver transplant patients and is beneficial for neurological recovery.

Original languageEnglish
Pages (from-to)E22513
JournalMedicine (United States)
Volume99
Issue number45
DOIs
StatePublished - 6 Nov 2020

Bibliographical note

Publisher Copyright:
Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc.

Keywords

  • cardiac arrest
  • liver regeneration
  • living-donor liver transplantation
  • therapeutic hypothermia

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