Urgent need for novel antibiotics in Republic of Korea to combat multidrug-resistant bacteria

Hyo Jin Lee, Dong Gun Lee

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations

Abstract

Multidrug resistance in bacteria is an important issue and is increasing in frequency worldwide because of the limitations of therapeutic agents. From 2010 to 2019, 14 new systemic antibiotics received regulatory approval in the United States. However, few new antibiotics have been introduced in Republic of Korea to combat multidrug-resistant pathogens. Here, we introduce six novel antibiotics for Gram-positive bacteria and five for Gram-negative bacteria approved by the United States Food and Drug Administration and the European Medicines Agency from 2009 to October 2021, and recommend that they be approved for use in Republic of Korea at the earliest possible date.

Original languageEnglish
Pages (from-to)271-280
Number of pages10
JournalKorean Journal of Internal Medicine
Volume37
Issue number2
DOIs
StatePublished - Mar 2022

Bibliographical note

Publisher Copyright:
© 2022 The Korean Association of Internal Medicine.

Keywords

  • Anti-bacterial agents
  • Antimicrobial stewardship
  • Carbapenem-resistant Enterobacteriaceae
  • Drug resistance, multiple
  • Methicillin-resistant Staphylococcus aureus

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