WNT3A expression is associated with MMP-9 expression in primary tumor and metastatic site in recurrent or stage IV colorectal cancer

  • Myung Ah Lee
  • , Jin Hee Park
  • , Si Young Rhyu
  • , Seong Taek Oh
  • , Won Kyoung Kang
  • , Hee Na Kim

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Colorectal cancer (CRC) is the 3rd most common cancer in Korea and is becoming more common in Asia and Western countries [1]. As new anti-cancer agents and new technology for local treatment have been developed, the survival rates of patients with CRC have been increasing, even for patients with stage IV cancer. However, distant organ metastasis eventually develops in stage IV cancer, and leads to fatal organ failure. To improve survival outcomes, it is important to control cancer invasion and metastasis, but the mechanisms by which CRC becomes metastasis are not yet known.

Original languageEnglish
Title of host publicationCancer Cell Signaling
Subtitle of host publicationTargeting Signaling Pathways Toward Therapeutic Approaches to Cancer
PublisherApple Academic Press
Pages81-96
Number of pages16
ISBN (Electronic)9781482299458
ISBN (Print)9781771880671
DOIs
StatePublished - 1 Jan 2014

Bibliographical note

Publisher Copyright:
© 2014 by Apple Academic Press, Inc.

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